ReviewGut2003
In vivo imaging with oligonucleotides for diagnosis and drug development.
Review in Gut, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Dynamic PET Imaging of EpCAM-Positive Colorectal Cancer Using Radiolabeled DTN-SYL3C Aptamer Conjugates.ACS omega · 2025Article
- A Historical Review of Brain Drug Delivery.Pharmaceutics · 2022Review
- Exploring the Structural Diversity of DNA Bottlebrush Polymers Using an Oligonucleotide Macromonomer Approach.Macromolecules · 2022Article
- Radiolabeling of functional oligonucleotides for molecular imaging.Frontiers in bioengineering and biotechnology · 2022Review
- Whole-body scanning PCR; a highly sensitive method to study the biodistribution of mRNAs, noncoding RNAs and therapeutic oligonucleotides.Nucleic acids research · 2013Article
- Radiolabeled oligonucleotides for antisense imaging.Current organic synthesis · 2011Article
- In vitro characterization of two novel biodegradable vectors for the delivery of radiolabeled antisense oligonucleotides.Cancer biotherapy & radiopharmaceuticals · 2010Article
- Automated synthesis of an 18F-labelled pyridine-based alkylating agent for high yield oligonucleotide conjugation.Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine · 2009Article
- Imaging oncogene expression.European journal of radiology · 2009Review
- Single-photon emission computed tomography in neurotherapeutics.NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics · 2005Review
- In vivo biodistribution and pharmacokinetics of 18F-labelled Spiegelmers: a new class of oligonucleotidic radiopharmaceuticals.European journal of nuclear medicine and molecular imaging · 2005Article
- Molecular imaging of atherosclerotic plaques with technetium-99m-labelled antisense oligonucleotides.European journal of nuclear medicine and molecular imaging · 2005Article
- Application of locked nucleic acids to improve aptamer in vivo stability and targeting function.Nucleic acids research · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Molecular imaging, the science that combines non-invasive in vivo imaging and molecular biology, has begun to use labelled oligonucleotides as radiotracers. Antisense oligonucleotides target gene expression at the RNA level, while aptamer oligonucleotides are designed to hit proteins of interest. Oligonucleotides for imaging cover a large range of applications, from the invention of new contrast agents for diagnosis to exquisite research tools for the development of new drugs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.