ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2003
High prevalence of superantigens associated with the egc locus in Staphylococcus aureus isolates from patients with atopic eczema.
Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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Who cites it
36 citing papers in PubMed.
- Multivalent nanobodies for potent and broad neutralization of Staphylococcus aureus toxins.Nature communications · 2026Article
- Article
- Staphylococcal Enterotoxins: Description and Importance in Food.Pathogens (Basel, Switzerland) · 2024Review
- Molecular characterization and antibiotic resistance ofFood science and biotechnology · 2024Article
- Enterotoxin Gene Cluster andCells · 2022Article
- Superantigens, a Paradox of the Immune Response.Toxins · 2022Review
- Methicillin-resistantVirulence · 2021Article
- Colonization WithFrontiers in microbiology · 2020Review
- High Prevalence ofGenes · 2019Article
- Characterization of Human Type C Enterotoxin Produced by Clinical S. epidermidis Isolates.Toxins · 2018Article
- Immunomodulation and Disease Tolerance to Staphylococcus aureus.Pathogens (Basel, Switzerland) · 2015Review
- [Atopic dermatitis in children. New aspects].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2015Review
- The role of antiseptic agents in atopic dermatitis.Asia Pacific allergy · 2014Review
- Staphylococcus aureus genomic pattern and atopic dermatitis: may factors other than superantigens be involved?European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2014Article
- ICON: chronic rhinosinusitis.The World Allergy Organization journal · 2014Article
- Staphylococcal Enterotoxin B-specific monoclonal antibody 20B1 successfully treats diverse Staphylococcus aureus infections.The Journal of infectious diseases · 2013Article
- Staphylococcus aureus clinical isolates: antibiotic susceptibility, molecular characteristics, and ability to form biofilm.BioMed research international · 2013Article
- An automated point-of-care system for immunodetection of staphylococcal enterotoxin B.Analytical biochemistry · 2011Article
- Characterization of virulence factors and genetic background of Staphylococcus aureus isolated from Peking University People's Hospital between 2005 and 2009.Current microbiology · 2010Article
- The role of 9-O-acetylated ganglioside D3 (CD60) and {alpha}4{beta}1 (CD49d) expression in predicting the survival of patients with Sezary syndrome.Haematologica · 2010Article
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9 authors.
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Abstract
The present study was aimed at identifying a possible correlation between disease severity and colonization with superantigen-producing Staphylococcus aureus strains in patients with atopic eczema. To this end, Staphylococcus aureus strains from 91 patients with atopic eczema were screened for various staphylococcal superantigens such as SEA, SEB, SEC, SED, TSST1, the recently described enterotoxin gene cluster egc (which encodes the enterotoxins SEG, SEI, SEK, SEM, and SEO), and the see, seh, and sej loci. Swabs were taken from seven different sites in each patient. The rate of colonization with Staphylococcus aureus was 87.9%. Of those patients colonized, 35% were colonized with more than one different strain. Of the 120 genetically different strains investigated, the egc locus was found in 48.3% and the sej locus in 7.5%. The see and seh loci were not found in any strain. The presence of the classical superantigens SEA-SED or TSST1 was found in 38.3%. Overall, 71.3% of the Staphylococcus aureus-positive patients harbored at least one superantigen-producing strain on their skin. There was no difference in the prevalence of superantigens between atopic eczema patients and healthy volunteers. Moreover, there was no difference in the extent of disease expression between patients colonized by superantigen-positive Staphylococcus aureus strains and those with superantigen-negative strains as measured by the SCORAD system. However, patients colonized with Staphylococcus aureus had a significantly higher SCORAD score than those not colonized.
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