ReviewNeurochemical research2003
Usefulness of behavioral and electrophysiological studies in transgenic models of Alzheimer's disease.
Review in Neurochemical research, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- Design and synthesis of neuroprotective methylthiazoles and modification as NO-chimeras for neurodegenerative therapy.Journal of medicinal chemistry · 2012Article
- APP transgenic mice for modelling behavioural and psychological symptoms of dementia (BPSD).Neuroscience and biobehavioral reviews · 2012Review
- Neurologic and motor dysfunctions in APP transgenic mice.Reviews in the neurosciences · 2012Review
- Endogenous amyloid-β is necessary for hippocampal synaptic plasticity and memory.Annals of neurology · 2011Article
- BACE and gamma-secretase characterization and their sorting as therapeutic targets to reduce amyloidogenesis.Neurochemical research · 2010Review
- Dysregulation of histone acetylation in the APP/PS1 mouse model of Alzheimer's disease.Journal of Alzheimer's disease : JAD · 2009Article
- Inhibition of calpains improves memory and synaptic transmission in a mouse model of Alzheimer disease.The Journal of clinical investigation · 2008Article
- Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Abeta accumulation.Proceedings of the National Academy of Sciences of the United States of America · 2008Article
- Cell cultures from animal models of Alzheimer's disease as a tool for faster screening and testing of drug efficacy.Journal of molecular neuroscience : MN · 2004Article
- Calpain inhibitors, a treatment for Alzheimer's disease: position paper.Journal of molecular neuroscience : MN · 2003Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the past several years researchers have engineered many transgenic models of Alzheimer's disease. Since loss of memory is one of the major hallmarks of the disorder, the phenotypic characterization of these animals has included both behavioral tests which aim to evaluate learning abilities, and electrophysiological studies to analyze synaptic transmission and long-term potentiation, a widely studied cellular model of learning and memory. These studies are fundamental for the design of novel therapies for the treatment and/or prevention of Alzheimer's disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.