ReviewNeurochemical research2003
In vivo NMR studies of neurodegenerative diseases in transgenic and rodent models.
Review in Neurochemical research, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Non-invasive assessment of disease progression and neuroprotective effects of dietary coconut oil supplementation in the ALS SOD1NeuroImage. Clinical · 2018Article
- Diverse application of MRI for mouse phenotyping.Birth defects research · 2017Review
- Metabolism changes during aging in the hippocampus and striatum of glud1 (glutamate dehydrogenase 1) transgenic mice.Neurochemical research · 2014Article
- Animal models and high field imaging and spectroscopy.Dialogues in clinical neuroscience · 2013Review
- In vivo high-resolution localized (1) H MR spectroscopy in the awake rat brain at 7 T.Magnetic resonance in medicine · 2013Article
- Article
- Effects of specific multi-nutrient enriched diets on cerebral metabolism, cognition and neuropathology in AβPPswe-PS1dE9 mice.PloS one · 2013Article
- MRI in rodent models of brain disorders.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2011Review
- Initial in vivo rodent sodium and proton MR imaging at 21.1 T.Magnetic resonance imaging · 2010Article
- Magnetic resonance spectroscopy of regional brain metabolite markers in FALS mice and the effects of dietary creatine supplementation.The European journal of neuroscience · 2009Article
- Article
- The application of NMR-based metabonomics in neurological disorders.NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics · 2006Review
- Magnetic resonance imaging, microscopy, and spectroscopy of the central nervous system in experimental animals.NeuroRx : the journal of the American Society for Experimental NeuroTherapeutics · 2005Review
- In vivo diffusion tensor mapping of the brain of squirrel monkey, rat, and mouse using single-shot STEAM MRI.Magma (New York, N.Y.) · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
In vivo magnetic resonance spectroscopy (MRS) and magnetic resonance imaging (MRI) provide unique quality to attain neurochemical, physiological, anatomical, and functional information non-invasively. These techniques have been increasingly applied to biomedical research and clinical usage in diagnosis and prognosis of diseases. The ability of MRS to detect early yet subtle changes of neurochemicals in vivo permits the use of this technology for the study of cerebral metabolism in physiological and pathological conditions. Recent advances in MR technology have further extended its use to assess the etiology and progression of neurodegeneration. This review focuses on the current technical advances and the applications of MRS and MRI in the study of neurodegenerative disease animal models including amyotrophic lateral sclerosis, Alzheimer's, Huntington's, and Parkinson's diseases. Enhanced MR measurable neurochemical parameters in vivo are described in regard to their importance in neurodegenerative disorders and their investigation into the metabolic alterations accompanying the pathogenesis of neurodegeneration.
Indexed as
Identifiers
12737523What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.