Evidence map›Paper›PMID 12736758›Full record

ReviewCurrent genetics2003

Evolution, biochemistry and genetics of protein kinase C in fungi.

Hans-Peter Schmitz, Jürgen J Heinisch

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current genetics, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. AssessingJournal of fungi (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hans-Peter SchmitzBiozentrum Basel, Institut für Angewandte Mikrobiologie, Bio-Pharmazentrum University of Basel, Klingelbergstrasse 50-70, 4056, Basel, Switzerland.
Jürgen J Heinisch

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

From yeast to humans, protein kinase C is an enzyme of central importance in signal transduction processes. In baker's yeast, Saccharomyces cerevisiae, a single gene encoding Pkc1p has been identified. Mutant analyses revealed that Pkc1p function is essential to ensure cellular integrity through regulation of a specific MAP kinase cascade. Due to the involvement of different defective mammalian isozymes in various diseases and the model character of simple eukaryotes, increasing attention has been paid to the structure and regulation of the enzymes of fungal origin. This review summarizes the knowledge gathered so far.

Indexed as

Amino Acid SequenceCysteineGene Expression Regulation, EnzymologicGene Expression Regulation, FungalMAP Kinase Signaling SystemModels, BiologicalMolecular Sequence DataMutationPhosphorylationProtein Kinase CProtein Structure, TertiarySaccharomyces cerevisiaeSequence Homology, Amino AcidSignal TransductionSpecies SpecificityYeastsCysteineProtein Kinase C

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.