Evidence map›Paper›PMID 12734583›Full record

ArticleBiological procedures online2001

Cytochemical techniques and energy-filtering transmission electron microscopy applied to the study of parasitic protozoa.

Marcos A Vannier-Santos, Ulysses Lins

Abstract read
In one paragraph

Article in Biological procedures online, 2001. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Quantum Biochemistry Screening and In Vitro Evaluation ofInternational journal of molecular sciences · 2022
    Article
  3. Article
  4. Ethanolic Extract of the FungusFrontiers in cellular and infection microbiology · 2020
    Article
  5. Article
  6. Article
  7. Article
  8. Protein turnover and differentiation in Leishmania.International journal for parasitology · 2007
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Marcos A Vannier-SantosLab. Biologia Celular Parasitária, Programa de Biologia Celular e Parasitologia, Instituto de Biofísica Carlos Chagas Filho. Universidade Federal do Rio de Janeiro, C.C.S. bloco G, Cidade Universitária, Ilha do Fundão, Rio de Janeiro, 21949-900. Brazil.Instituto de Microbiologia Prof. Paulo de Góes. Universidade Federal do Rio de Janeiro. Brazil. vannier@biof.ufrj.br
Ulysses Lins

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The study of parasitic protozoa plays a major role in cell biology, biochemistry and molecular biology. Numerous cytochemical techniques have been developed in order to unequivocally identify the nature of subcellular compartments. Enzyme and immuno-cytochemistry allow the detection of, respectively, enzymatic activity products and antigens in particular sites within the cell. Energy-filtering transmission electron microscopy permits the detection of specific elements within such compartments. These approaches are particularly useful for studies employing antimicrobial agents where cellular compartments may be destroyed or remarkably altered and thus hardly identified by standard methods of observation. In this regard cytochemical and spectroscopic techniques provide valuable data allowing the determination of the mechanisms of action of such compounds.

Identifiers

PMID12734583
PMCPMC145542

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.