Trial reportJournal of perinatology : official journal of the California Perinatal Association
Usefulness of the minute ventilation test in predicting successful extubation in newborn infants: a randomized controlled trial.
Trial report in Journal of perinatology : official journal of the California Perinatal Association. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- Protocolized versus non-protocolized weaning for reducing the duration of invasive mechanical ventilation in newborn infants.The Cochrane database of systematic reviews · 2016Pooled it
- Extubation from low-rate intermittent positive airways pressure versus extubation after a trial of endotracheal continuous positive airways pressure in intubated preterm infants.The Cochrane database of systematic reviews · 2000Pooled it
- High-flow nasal cannula and extubation success in the premature infant: a comparison of two modalities.Journal of perinatology : official journal of the California Perinatal Association · 2010Trial
- Predictors of successful extubation from volume-targeted ventilation in extremely preterm neonates.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Weaning and extubation from neonatal mechanical ventilation: an evidenced-based review.BMC pulmonary medicine · 2022Review
- Can Fraction of Inspired Oxygen Predict Extubation Failure in Preterm Infants?Children (Basel, Switzerland) · 2022Article
- Accuracy of Spontaneous Breathing Trial Using ET-CPAP in Predicting Successful Extubation of Neonates.Cureus · 2021Article
- Extubation Readiness in Preterm Infants: Evaluating the Role of Monitoring Intermittent Hypoxemia.Children (Basel, Switzerland) · 2021Article
- Relationship Between the Respiratory Severity Score and Extubation Failure in Very-Low-Birth-Weight Premature Infants.Sisli Etfal Hastanesi tip bulteni · 2021Article
- Effects of an extubation readiness test protocol at a tertiary care fully outborn neonatal intensive care unit.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2019Article
- Effect of Anatomical and Developmental Factors on the Risk of Unplanned Extubation in Critically Ill Newborns.American journal of perinatology · 2017Article
- Prediction of Extubation readiness in extremely preterm infants by the automated analysis of cardiorespiratory behavior: study protocol.BMC pediatrics · 2017Observational
- Effects of Multiple Ventilation Courses and Duration of Mechanical Ventilation on Respiratory Outcomes in Extremely Low-Birth-Weight Infants.JAMA pediatrics · 2015Article
- Effects of therapeutic hypothermia on multiorgan dysfunction in asphyxiated newborns: whole-body cooling versus selective head cooling.Journal of perinatology : official journal of the California Perinatal Association · 2009Article
- Predicting successful extubation of very low birthweight infants.Archives of disease in childhood. Fetal and neonatal edition · 2006Article
- Mechanical ventilation weaning practices in neonatal and pediatric ICUs in Brazil: the Weaning Survey-Brazil.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e TisilogiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe performed a prospective, randomized clinical trial to compare the usefulness of the minute ventilation test (MVT) with clinical judgement in predicting readiness for extubation in preterm newborns with respiratory distress syndrome requiring surfactant therapy and mechanical ventilation. STUDY
designA total of 42 preterm infants with respiratory distress syndrome were randomized when they reached preselected ventilator settings. The primary outcome measure was the time from study entry to extubation, provided the infant remained extubated for at least 24 hours.
resultsInfants evaluated by the MVT were extubated in a significantly shorter period of time (mean of 8 hours) than those evaluated clinically (mean of 36 hours). The extubation failure rate was similar in the two groups.
conclusionThe MVT is an easily performed objective measure that can be used to predict readiness for extubation in preterm infants. In this study, it significantly shortened the time for extubation and was not associated with a higher rate of reintubation.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.