ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2003
Skeletal status in males aged 7-80 years assessed by quantitative ultrasound at the hand phalanges.
Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
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4 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- [Factors that influence bone mass of healthy children and adolescents measured by quantitative ultrasound at the hand phalanges: a systematic review].Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2014Pooled it
- Quantitative Ultrasound Examination (QUS) of the Calcaneus in Long-Term Martial Arts Training on the Example of Long-Time Practitioners of Okinawa Kobudo/Karate Shorin-Ryu.International journal of environmental research and public health · 2023Article
- Brazilian pediatric reference data for quantitative ultrasound of phalanges according to gender, age, height and weight.PloS one · 2015Article
- Reference data for quantitative ultrasound values of calcaneus in 2927 healthy Chinese men.Journal of bone and mineral metabolism · 2008Article
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Authors and funding
2 authors at 1 institution in 1 country.
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Abstract
Skeletal status in males has been assessed by quantitative ultrasound in only a few studies. There is the lack of data concerning age accretion, peak values, and age-decrease of bone parameters in a wide age range. The aim of this study was evaluation of a large, male, normal population (n=1,175) aged 7-80 years, by the use of quantitative ultrasound (QUS), to estimate peak value of phalangeal ultrasound parameter, age-related changes during growing and aging, the influence of body size, and determination of male normative data. In the study, amplitude-dependent speed of sound (Ad-SoS) at the hand phalanges was measured using DBM Sonic 1200 (IGEA, Italy). The precision assessed by root-mean-square coefficient of variation (RMS-CV) was 0.7%. Ad-SoS ranged from 1,916 m/s in the youngest subgroup (7 years of age) to 1,910 m/s in the oldest (75-80 years of age), and the peak value (2,135 m/s) was achieved in 28-year-old males. Ad-SoS did not increase significantly to the age of 13. Ad-SoS increased significantly between subgroups aged 13 and 14 years ( p<0.0001), and at 15 and 16 years of age ( p<0.000001). A significant decrease was noted between the following age subgroups: 35-39 years vs 40-44 years ( p<0.05), 45-49 years vs 50-54 years ( p<0.000001), and 60-64 years vs 65-69 years ( p<0.001). A difference in Ad-SoS values between the youngest subgroup and peak value was 219 m/s, and an increase per year was about 10.4 m/s. From the peak value to the value in the oldest group Ad-SoS dropped by 225 m/s, and the decrease per year was about 4.6 m/s. Multiple stepwise regression analyses of Ad-SoS with age, weight,and height were performed separately for age ranges: 7-13 years (before an increase in Ad-SoS, n=299), 14-28 years (from the onset of the fast increase in Ad-SoS to the peak value, n=370) and for subjects older than 28 years (after an achievement of peak value of Ad-SoS, n=506). The following equations of the multiple stepwise regression were obtained, respectively: Ad-SoS (m/s)=1,624-1.0 x age (years) -2.94 x weight (kg) + 3.06 x height (cm), r=0.48, p<0.000001, SEE=32.0; Ad-SoS (m/s)=1,533+6.87 x age (years) + 2.41 x height (cm) 0.07 x weight (kg), r=0.56, p<0.000001, SEE=54.3; Ad-SoS (m/s)=1,895-3.87 x age (years) - 1.43 x weight (kg) + 2.53 x height (cm), r=0.73, p<0.00001, SEE=54.3. In conclusion, the study results allowed us to determine normative data, to assess a peak Ad-SoS value, its age-related changes and the influence of body size in the male population.
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