ArticlePlanta2003
Overproduced ethylene causes programmed cell death leading to temperature-sensitive lethality in hybrid seedlings from the cross Nicotiana suaveolens x N. tabacum.
Article in Planta, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 44 citations in OpenAlex.
- Graft compatibility emerges from the balance between regeneration and immunity: lessons from plant-plant interactions.Frontiers in plant science · 2026Review
- Genome-shock deletion of a hybrid lethality gene breaks a reproductive barrier and facilitates speciation inFrontiers in plant science · 2025Article
- A chemical approach to extend flower longevity of Japanese morning glory via inhibition of master senescence regulator EPHEMERAL1.Nature plants · 2024Article
- Understanding and overcoming hybrid lethality in seed and seedling stages as barriers to hybridization and gene flow.Frontiers in plant science · 2023Review
- The hybrid lethality of interspecific FMolecular breeding : new strategies in plant improvement · 2022Review
- Genetic Mapping of thePlants (Basel, Switzerland) · 2021Article
- Characterization of transcriptomic response in ovules derived from inter-subgeneric hybridization in Prunus (Rosaceae) species.Plant reproduction · 2021Article
- Article
- A Novel Embryo Phenotype Associated With Interspecific Hybrid Weakness in Rice Is Controlled by the MADS-Domain Transcription FactorFrontiers in plant science · 2021Article
- Phenylalanine ammonia-lyase and phenolic compounds are related to hybrid lethality in the crossPlant biotechnology (Tokyo, Japan) · 2020Article
- Article
- Tumorigenesis inheritance from the putative progenitor species ofPlant biotechnology (Tokyo, Japan) · 2017Article
- Ethylene Antagonizes Salt-Induced Growth Retardation and Cell Death Process via Transcriptional Controlling of Ethylene-, BAG- and Senescence-Associated Genes in Arabidopsis.Frontiers in plant science · 2016Article
- Seven of eight species in Nicotiana section Suaveolentes have common factors leading to hybrid lethality in crosses with Nicotiana tabacum.Annals of botany · 2010Article
- Interaction of novel Dobzhansky-Muller type genes for the induction of hybrid lethality between Gossypium hirsutum and G. barbadense cv. Coastland R4-4.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2009Article
- InPSR26, a putative membrane protein, regulates programmed cell death during petal senescence in Japanese morning glory.Plant physiology · 2009Article
- Identification and characterization of genes involved in hybrid lethality in hybrid tobacco cells (Nicotiana suaveolens x N. tabacum) using suppression subtractive hybridization.Plant cell reports · 2007Article
- Autoimmune response as a mechanism for a Dobzhansky-Muller-type incompatibility syndrome in plants.PLoS biology · 2007Article
- Article
- Nuclear fragmentation and DNA degradation during programmed cell death in petals of morning glory (Ipomoea nil).Planta · 2006Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reproductive isolation mechanisms (RIMs) often become obstacles in crossbreeding. Hybrid lethality is a subtype of RIM but its physiological mechanism remains poorly elucidated. Interspecific hybrids of Nicotiana suaveolens Lehm. x N. tabacum L. cv. Hicks-2 expressed temperature-sensitive lethality. This lethality was induced by programmed cell death (PCD) that was accompanied by the characteristic changes of animal apoptosis in hybrid seedlings at 28 degrees C but not at 36 degrees C. When hybrid seedlings were cultured at 28 degrees C, DNA fragmentation started in the cotyledon, and nuclear fragmentation subsequently progressed with lethal symptoms spreading throughout the seedlings. At 28 degrees C, ethylene production in hybrid seedlings was detectable at a high level compared with the level in parental seedlings. In contrast, the ethylene production rate in hybrid seedlings cultured at 36 degrees C was equal to that in parental seedlings. Treatment with ethylene biosynthetic inhibitors, amino-oxyacetic acid and amino-ethoxyvinyl glycine, suppressed lethal symptoms and apoptotic changes, and also prolonged survival of hybrid seedlings. Thus, the increase in the ethylene production rate correlated closely with expression of lethal symptoms and apoptotic changes in hybrid seedlings. From these observations, we conclude that overproduced ethylene acts as an essential factor mediating PCD and subsequent lethality in hybrid seedlings. Furthermore, the present study has provided the first evidence that ethylene is involved in the phenomenon of hybrid lethality.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.