ArticleEnvironmental health perspectives2003
Health impacts of pesticide exposure in a cohort of outdoor workers.
Article in Environmental health perspectives, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 4 syntheses or guidelines pooled it, 133 citations in OpenAlex.
- Duration-response association between occupational exposure and pancreatic cancer risk: meta-analysis.Occupational medicine (Oxford, England) · 2023Pooled it
- Association between pesticide exposure and colorectal cancer risk and incidence: A systematic review.Ecotoxicology and environmental safety · 2021Pooled it
- Is pesticide exposure a cause of obstructive airways disease?European respiratory review : an official journal of the European Respiratory Society · 2014Pooled it
- Cancer health effects of pesticides: systematic review.Canadian family physician Medecin de famille canadien · 2007Pooled it
- Trial
- High-Fat Diet Aggravates the Disorder of Glucose Metabolism Caused by Chlorpyrifos Exposure in Experimental Rats.Foods (Basel, Switzerland) · 2023Article
- Plasma concentrations of lipophilic persistent organic pollutants and glucose homeostasis in youth populations.Environmental research · 2022Article
- Exocrine pancreatic cancer and living near to waste sites containing hazardous organic chemicals, New York State, USA - an 18-year population-based study.International journal of occupational medicine and environmental health · 2022Article
- Insecticide Exposure and Risk of Asthmatic Symptoms: A Systematic Review and Meta-Analysis.Toxics · 2021Review
- Protective effect of thymoquinone against lung intoxication induced by malathion inhalation.Scientific reports · 2021Article
- Occupational Risk Factors for Prostate Cancer: A Meta-analysis.Journal of cancer prevention · 2019Review
- Association of Exposure to Persistent Organic Pollutants With Mortality Risk: An Analysis of Data From the Prospective Investigation of Vasculature in Uppsala Seniors (PIVUS) Study.JAMA network open · 2019Article
- Pesticide Use and Asthma in Alberta Grain Farmers.International journal of environmental research and public health · 2018Article
- Association between diabetes and pesticides: a case-control study among Thai farmers.Environmental health and preventive medicine · 2018Article
- Organochlorine pesticide residues in dried cocoa beans obtained from cocoa stores at Ondo and Ile-Ife, Southwestern Nigeria.Toxicology reports · 2017Article
- Visceral Leishmaniasis on the Indian Subcontinent: Modelling the Dynamic Relationship between Vector Control Schemes and Vector Life Cycles.PLoS neglected tropical diseases · 2016Article
- Occupational exposure to pesticides and respiratory health.European respiratory review : an official journal of the European Respiratory Society · 2015Review
- Association between lung function in adults and plasma DDT and DDE levels: results from the Canadian Health Measures Survey.Environmental health perspectives · 2015Article
- Obesity and diabetes: from genetics to epigenetics.Molecular biology reports · 2015Article
- Pesticides and asthma: challenges for epidemiology.Frontiers in public health · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We compared mortality of 1,999 outdoor staff working as part of an insecticide application program during 1935-1996 with that of 1,984 outdoor workers not occupationally exposed to insecticides, and with the Australian population. Surviving subjects also completed a morbidity questionnaire. Mortality was significantly higher in both exposed and control subjects compared with the Australian population. The major cause was mortality from smoking-related diseases. Mortality was also significantly increased in exposed subjects for a number of conditions that do not appear to be the result of smoking patterns. Compared with the general Australian population, mortality over the total study period was increased for asthma [standardized mortality ratio (SMR) = 3.45; 95% confidence interval (CI), 1.39-7.10] and for diabetes (SMR = 3.57; 95% CI, 1.16-8.32 for subjects working < 5 years). Mortality from pancreatic cancer was more frequent in subjects exposed to 1,1,1-trichloro-2,2-bis(p-chlorophenyl)ethane (SMR = 5.27; 95% CI, 1.09-15.40 for subjects working < 3 years). Compared with the control population, mortality from leukemia was increased in subjects working with more modern chemicals (standardized incidence ratio = 20.90; 95% CI, 1.54-284.41 for myeloid leukemia in the highest exposure group). There was also an increase in self-reported chronic illness and asthma, and lower neuropsychologic functioning scores among surviving exposed subjects when compared with controls. Diabetes was reported more commonly by subjects reporting occupational use of herbicides. These findings lend weight to other studies suggesting an association between adverse health effects and exposure to pesticides.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.