ArticleMolecular genetics and genomics : MGG2003
The cold-regulated transcriptional activator Cbf3 is linked to the frost-tolerance locus Fr-A2 on wheat chromosome 5A.
Article in Molecular genetics and genomics : MGG, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 89 papers.
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89 citing papers in PubMed, 241 citations in OpenAlex.
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- Allelic variation at a single locus distinguishes spring and winter faba beans.Nature genetics · 2026Article
- Genome-wide association mapping and candidate genes analysis of high-throughput image descriptors for wheat frost tolerance.Stress biology · 2025Article
- Genome-wide association analysis of winter survival in a diverse Canadian winter wheat population.The plant genome · 2025Article
- Multi-omics analysis reveals the physiological and molecular response to cold stress in different spring wheat cultivars at the booting stage.Frontiers in plant science · 2025Article
- Advances and opportunities in unraveling cold-tolerance mechanisms in the world's primary staple food crops.The plant genome · 2024Review
- A large-effect fitness trade-off across environments is explained by a single mutation affecting cold acclimation.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Molecular mapping of two novel cold resistance genes in common wheat by 660K SNP array.Molecular breeding : new strategies in plant improvement · 2023Article
- TheCells · 2023Review
- Identification of Novel QTLs Associated with Frost Tolerance in Winter Wheat (Plants (Basel, Switzerland) · 2023Article
- Physiology and Molecular Breeding in Sustaining Wheat Grain Setting and Quality under Spring Cold Stress.International journal of molecular sciences · 2022Review
- Genome wide association study of frost tolerance in wheat.Scientific reports · 2022Article
- Extensive allele mining discovers novel genetic diversity in the loci controlling frost tolerance in barley.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2022Article
- Quantitative trait loci and candidate genes associated with freezing tolerance of winter triticale (× Triticosecale Wittmack).Journal of applied genetics · 2022Article
- Computational genomics insights into cold acclimation in wheat.Frontiers in genetics · 2022Article
- A QTL approach in faba bean highlights the conservation of genetic control of frost tolerance among legume species.Frontiers in plant science · 2022Article
- Capturing Wheat Phenotypes at the Genome Level.Frontiers in plant science · 2022Review
- Identification of genetic loci associated with major agronomic traits of wheat (Triticum aestivum L.) based on genome-wide association analysis.BMC plant biology · 2021Article
- The Breeding of Winter-Hardy Malting Barley.Plants (Basel, Switzerland) · 2021Review
- Relationship between WCS120 Protein Family Accumulation and Frost Tolerance in Wheat Cultivars Grown under Different Temperature Treatments.Plants (Basel, Switzerland) · 2021Article
29 more citing papers are in PubMed but not listed here.
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4 authors at 3 institutions in 3 countries.
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Abstract
Wheat chromosome 5A plays a key role in cold acclimation and frost tolerance. The major frost tolerance gene Fr-A1(formerly Fr1) and two loci that regulate the transcription of cold- regulated genes (Cor) have previously been mapped on the long arm of this chromosome. In this study we report the discovery of a new locus for frost tolerance designated Fr-A2. This new locus was mapped on the long arm of chromosome 5A of diploid wheat (T. monococcum), 40 cM from the centromere and 30 cM proximal to the major frost tolerance locus Fr-A1. We found also that frost-tolerant and frost-susceptible T. monococcum parental lines differed in the transcription level of the cold induced gene Cor14b when plants were grown at 15 degrees C. Transcription levels of this gene were measured in each of the recombinant inbred lines and mapped as a QTL that perfectly overlapped the QTL for frost survival at the Fr-A2 locus. This result suggested that frost tolerance in this cross was mediated by differential regulation of the expression of the Corgenes. In a previous study in hexaploid wheat (T. aestivum) we had shown that Cor14b was regulated by two loci located on chromosome 5A, one in the same chromosome region as the T. monococcum Fr-A2 locus and the other one closely linked to Fr-A1. Since CBF transcriptional activators in Arabidopsis regulate Corgenes and are involved in frost tolerance, we decided to localize the cold-regulated CBF-like barley gene Cbf3 on the T. monococcum map. This gene was mapped on the peak of the Fr-A2 QTL for frost tolerance. This result suggests that the observed differential regulation of Cor14b at the Fr-A2 locus is due to allelic variation at the XCbf3 locus, and that this transcriptional activator gene might be a candidate gene for the Fr-A2 frost tolerance locus on wheat chromosome 5A.
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