ReviewJournal of anatomy2003
Concordia discors: duality in the origin of the vertebrate tail.
Review in Journal of anatomy, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 58 citations in OpenAlex.
- Secondary neurulation mechanisms likely arose in vertebrates during mesenchymal tailbud extension.Frontiers in cell and developmental biology · 2026Article
- Article
- Protein signaling and morphological development of the tail fluke in the embryonic beluga whale (Delphinapterus leucas).Developmental dynamics : an official publication of the American Association of Anatomists · 2024Article
- Constructing the pharyngula: Connecting the primary axial tissues of the head with the posterior axial tissues of the tail.Cells & development · 2023Review
- Article
- Hallmarks of primary neurulation are conserved in the zebrafish forebrain.Communications biology · 2021Article
- Stem Cell Neurodevelopmental Solutions for Restorative Treatments of the Human Trunk and Spine.Frontiers in cellular neuroscience · 2021Article
- The Enigmatic Reissner's Fiber and the Origin of Chordates.Frontiers in neuroanatomy · 2021Review
- Anteroposterior Wnt-RA Gradient Defines Adhesion and Migration Properties of Neural Progenitors in Developing Spinal Cord.Stem cell reports · 2020Article
- The vertebrate tail: a gene playground for evolution.Cellular and molecular life sciences : CMLS · 2020Review
- Substrate use drives the macroevolution of mammalian tail length diversity.Proceedings. Biological sciences · 2020Article
- Posterior tail development in the salamander Eurycea cirrigera: exploring cellular dynamics across life stages.Development genes and evolution · 2017Article
- Neuromesodermal progenitors and the making of the spinal cord.Development (Cambridge, England) · 2015Review
- From dinosaurs to birds: a tail of evolution.EvoDevo · 2014Review
- Proceedings of the 2013 National Toxicology Program Satellite Symposium.Toxicologic pathology · 2014Article
- The neural crest and neural crest cells: discovery and significance for theories of embryonic organization.Journal of biosciences · 2008Review
- Early Palaeozoic dentine and patterned scales in the embryonic catshark tail.Biology letters · 2008Article
- Mechanisms driving neural crest induction and migration in the zebrafish and Xenopus laevis.Cell adhesion & migrationReview
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The vertebrate tail is an extension of the main body axis caudal to the anus. The developmental origin of this structure has been a source of debate amongst embryologists for the past century. Some view tail development as a continuation of the morphogenetic processes that shape the head and trunk (i.e. gastrulation). The alternative view, secondary development, holds that the tail forms in a manner similar to limb development, i.e. by secondary induction. Previous developmental studies have provided support for both views. Here I revisit these studies, describing caudal morphogenesis in select vertebrates, the associated genes and developmental defects, and, as a relevant aside, consider the developmental and evolutionary relationships of primary and secondary neurulation. I conclude that caudal development enlists both gastrulation and secondary induction, and that the application of recent high-resolution cell labelling technology may clarify how these discordant programmes interact in building the vertebrate tail.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.