ArticleNucleic acids research2003
Sequence and structure of the extrachromosomal palindrome encoding the ribosomal RNA genes in Dictyostelium.
Article in Nucleic acids research, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 53 citations in OpenAlex.
- Telomere-to-telomere characterization of rDNA chromosome in the myxomycete Didymium iridis.BMC molecular and cell biology · 2026Article
- Fractional 2'-O-methylation in the ribosomal RNA of Dictyostelium discoideum supports ribosome heterogeneity in Amoebozoa.Scientific reports · 2022Article
- Investigation of the host transcriptional response to intracellular bacterial infection using Dictyostelium discoideum as a host model.BMC genomics · 2019Article
- Triparental inheritance inProceedings of the National Academy of Sciences of the United States of America · 2019Article
- dictyBase and the Dicty Stock Center (version 2.0) - a progress report.The International journal of developmental biology · 2019Review
- Structure of Dictyostelium discoideum telomeres. Analysis of possible replication mechanisms.PloS one · 2019Article
- The Long Noncoding RNA Transcriptome ofG3 (Bethesda, Md.) · 2017Article
- Retrotransposon Domestication and Control inFrontiers in microbiology · 2017Review
- Article
- The C-Terminal SynMuv/DdDUF926 Domain Regulates the Function of the N-Terminal Domain of DdNKAP.PloS one · 2016Article
- A deep coverage Dictyostelium discoideum genomic DNA library replicates stably in Escherichia coli.Genomics · 2015Article
- One stop shop for everything Dictyostelium: dictyBase and the Dicty Stock Center in 2012.Methods in molecular biology (Clifton, N.J.) · 2013Article
- DictyBase 2013: integrating multiple Dictyostelid species.Nucleic acids research · 2013Article
- Phylogeny-wide analysis of social amoeba genomes highlights ancient origins for complex intercellular communication.Genome research · 2011Article
- Genetically tagged TRE5-A retrotransposons reveal high amplification rates and authentic target site preference in the Dictyostelium discoideum genome.Nucleic acids research · 2011Article
- Sequence and generation of mature ribosomal RNA transcripts in Dictyostelium discoideum.The Journal of biological chemistry · 2011Article
- dictyBase update 2011: web 2.0 functionality and the initial steps towards a genome portal for the Amoebozoa.Nucleic acids research · 2011Article
- dictyBase--a Dictyostelium bioinformatics resource update.Nucleic acids research · 2009Article
- De novo search for non-coding RNA genes in the AT-rich genome of Dictyostelium discoideum: performance of Markov-dependent genome feature scoring.Genome research · 2008Article
- The small RNA repertoire of Dictyostelium discoideum and its regulation by components of the RNAi pathway.Nucleic acids research · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 1 institution in 1 country.
Funding
Abstract
Ribosomal RNAs (rRNAs) are encoded by multicopy families of identical genes. In Dictyostelium and other protists, the rDNA is carried on extrachromosomal palindromic elements that comprise up to 20% of the nuclear DNA. We present the sequence of the 88 kb Dictyostelium rDNA element, noting that the rRNA genes are likely to be the only transcribed regions. By interrogating a library of ordered YAC clones, we provide evidence for a chromosomal copy of the rDNA on chromosome 4. This locus may provide master copies for the stable transmission of the extrachromosomal elements. The extrachromosomal elements were also found to form chromosome-sized clusters of DNA within nuclei of nocodazole-treated cells arrested in mitosis. These clusters resemble true chromosomes and may allow the efficient segregation of the rDNA during mitosis. These rDNA clusters may also explain the cytological observations of a seventh chromosome in this organism.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.