Evidence map›Paper›PMID 12710797›Full record

ReviewMaternal and child health journal2003

Racial and ethnic disparities in birth outcomes: a life-course perspective.

Michael C Lu, Neal Halfon

Abstract readReview
PubMed Publisher
In one paragraph

Review in Maternal and child health journal, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 473 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
473citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

473 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Spatial Logic and Evolutionary Innovation in Human Placentation.bioRxiv : the preprint server for biology · 2026
    Article
  8. Article
  9. Article
  10. Race, Place and Preterm Birth.Paediatric and perinatal epidemiology · 2026
    Article
  11. Article
  12. Article
  13. Article
  14. Psychological Impacts of Premature Birth on Mothers: A Literature Review.Advances in experimental medicine and biology · 2026
    Review
  15. Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article

413 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Michael C LuDepartment of Obstetrics & Gynecology, Center for Healthier Children, Families, and Communities, UCLA School of Medicine, Los Angeles, California, USA. mclu@ucla.edu
Neal Halfon

Funding

NICHD NIH HHS HD01281-03PHS HHS 5U93MC00099
6 · The paper itself

Abstract

backgroundIn the United States, Black infants have significantly worse birth outcomes than do White infants. The cause of these persisting racial disparities remains unexplained. Most extant studies focus on differential exposures to protective and risk factors during pregnancy, such as current socioeconomic status, maternal risky behaviors, prenatal care, psychosocial stress, or perinatal infections. These risk factors during pregnancy, however, do not adequately account for the disparities.

methodsWe conducted a literature review for longitudinal models of health disparities, and presented a synthesis of two leading models, using a life-course perspective. Traditional risk factors during pregnancy are then reexamined within their life-course context. We conclude with a discussion of the limitations and implications of the life-course perspective for future research, practice, and policy development.

resultsTwo leading longitudinal models of health disparities were identified and discussed. The early programming model posits that exposures in early life could influence future reproductive potential. The cumulative pathways model conceptualizes decline in reproductive health resulting from cumulative wear and tear to the body's allostatic systems. We propose a synthesis of these two models, using the life-course perspective. Disparities in birth outcomes are the consequences of differential developmental trajectories set forth by early life experiences and cumulative allostatic load over the life course.

conclusionsFuture research on racial disparities in birth outcomes needs to examine differential exposures to risk and protective factors not only during pregnancy, but over the life course of women. Eliminating disparities requires interventions and policy development that are more longitudinally and contextually integrated than currently prevail.

Indexed as

Life TablesModels, TheoreticalRacial GroupsWomen's HealthBlack or African AmericanFemaleHealth BehaviorHealth Services AccessibilityHumansInfant MortalityInfant, NewbornLongitudinal StudiesMaternal WelfarePregnancyPregnancy OutcomeQuality of Health Care

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.