ArticleOccupational and environmental medicine2003
Breast cancer and serum organochlorine residues.
Article in Occupational and environmental medicine, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 117 citations in OpenAlex.
- The Relationship Between Climate Change and Breast Cancer and Its Management and Preventative Implications in South Africa.International journal of environmental research and public health · 2025Pooled it
- DDT/DDE and breast cancer: a meta-analysis.Regulatory toxicology and pharmacology : RTP · 2013Pooled it
- Human health risk assessment of dichlorodiphenyltrichloroethane (DDT) and hexachlorocyclohexane (HCH) pesticide residues in fruits and vegetables in Nigeria.Environmental science and pollution research international · 2021Article
- Exposure to organochlorine pesticides as a predictor to breast cancer: A case-control study among Ethiopian women.PloS one · 2021Article
- Aryl Hydrocarbon Receptor Connects Inflammation to Breast Cancer.International journal of molecular sciences · 2020Review
- Serum concentrations of DDE, PCBs, and other persistent organic pollutants and mammographic breast density in Triana, Alabama, a highly exposed population.Environmental research · 2020Article
- Self-reported residential pesticide use and survival after breast cancer.International journal of hygiene and environmental health · 2019Article
- Persistent Organic Pollutants and Breast Cancer: A Systematic Review and Critical Appraisal of the Literature.Cancers · 2019Review
- Serum concentrations of selected organochlorine pesticides in a Lebanese population and their associations to sociodemographic, anthropometric and dietary factors: ENASB study.Environmental science and pollution research international · 2018Article
- Is there a genetic anticipation in breast and/or ovarian cancer families with the germline c.3481_3491del11 mutation?Familial cancer · 2018Article
- Carcinogenetic mechanisms of endocrine disruptors in female cancers (Review).Oncology reports · 2016Review
- Childhood and Adolescent Pesticide Exposure and Breast Cancer Risk.Epidemiology (Cambridge, Mass.) · 2016Article
- Organochlorine insecticides DDT and chlordane in relation to survival following breast cancer.International journal of cancer · 2016Article
- Human Elimination of Organochlorine Pesticides: Blood, Urine, and Sweat Study.BioMed research international · 2016Article
- Complex organochlorine pesticide mixtures as determinant factor for breast cancer risk: a population-based case-control study in the Canary Islands (Spain).Environmental health : a global access science source · 2012Article
- Associations of serum concentrations of organochlorine pesticides with breast cancer and prostate cancer in U.S. adults.Environmental health perspectives · 2010Article
- Physiologically based pharmacokinetic modeling of persistent organic pollutants for lifetime exposure assessment: a new tool in breast cancer epidemiologic studies.Environmental health perspectives · 2008Article
- Residential proximity to agricultural pesticide use and incidence of breast cancer in California, 1988-1997.Environmental health perspectives · 2005Article
- Breast cancer risk and historical exposure to pesticides from wide-area applications assessed with GIS.Environmental health perspectives · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundControversy still exists about the breast carcinogenic properties in humans of environmental xenoestrogens (organochlorines), justifying new investigations.
aimsTo compare the blood levels of total dichlorodiphenyltrichloroethane (DDT) and hexachlorobenzene (HCB) in samples collected at the time of breast cancer discovery, in order to avoid the potential consequences of body weight change (after chemotherapy or radiotherapy) on the pesticide residue levels.
methodsBlood levels of HCB and total DDT (we calculated total DDT concentrations by adding all DDT and DDE isomers) were compared in 159 women with breast cancer and 250 presumably healthy controls. Risk of breast cancer associated with organochlorine concentration was evaluated.
resultsMean levels of total DDT and HCB were significantly higher for breast cancer patients than for controls. No differences in serum levels of total DDT or HCB were found between oestrogen receptor positive and oestrogen receptor negative patients with breast cancer.
conclusionsThese results add to the growing evidence that certain persistent pollutants may occur in higher concentrations in blood samples from breast cancer patients than controls.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.