Evidence map›Paper›PMID 12707779›Full record

ArticleChromosoma2003

Analysis of the distribution of the kinetochore protein Ndc10p in Saccharomyces cerevisiae using 3-D modeling of mitotic spindles.

Thomas Müller-Reichert, Ingrid Sassoon, Eileen O'Toole, Maryse Romao, Anthony J Ashford, Anthony A Hyman, Claude Antony

Abstract read
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In one paragraph

Article in Chromosoma, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. The kinetochore protein Ndc10p is required for spindle stability and cytokinesis in yeast.Proceedings of the National Academy of Sciences of the United States of America · 2005
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Thomas Müller-ReichertMax Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany. mueller-reichert@mpi-cbg.de
Ingrid Sassoon
Eileen O'Toole
Maryse Romao
Anthony J Ashford
Anthony A Hyman
Claude Antony

Funding

WORKSHOPS AND TRAINING FOR IMAGE ANALYSIS USING IMODP41RR000592 · NCRR · UNIVERSITY OF COLORADO AT BOULDER · PI BASS, PETER W. · 1985 to 2011
$11.9M
NCRR NIH HHS RR-0592
6 · The paper itself

Abstract

Ndc10p is one of the DNA-binding constituents of the kinetochore in Saccharomyces cerevisiae but light microscopy analysis suggests that Ndc10p is not limited to kinetochore regions. We examined the localization of Ndc10p using immunoelectron microscopy and showed that Ndc10p is associated with spindle microtubules from S-phase through anaphase. By serial section reconstruction of mitotic spindles combined with immunogold detection, we showed that Ndc10p interacts with microtubules laterally as well as terminally. About 50% of the gold label in serial section reconstructions of short mitotic spindles was associated with the walls of spindle microtubules. Interaction of kinetochore components with microtubule walls was also shown for kinetochore protein Ndc80p. Our data suggest that at least a subset of kinetochore-associated protein is dispersed throughout the mitotic spindle.

Indexed as

Spindle ApparatusAnaphaseCentromereDNA-Binding ProteinsImmunohistochemistryKinetochoresMicroscopy, ElectronMicroscopy, ImmunoelectronMicrotubulesMitosisNuclear ProteinsProtein BindingSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsS PhaseCBF2 protein, S cerevisiaeDNA-Binding ProteinsNDC80 protein, S cerevisiaeNuclear ProteinsSaccharomyces cerevisiae Proteins

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.