ReviewPflugers Archiv : European journal of physiology2003
Potassium channels in epithelial transport.
Review in Pflugers Archiv : European journal of physiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 56 citations in OpenAlex.
- KCNJ16-depleted kidney organoids recapitulate tubulopathy and lipid recovery upon statins treatment.Stem cell research & therapy · 2024Article
- EAST/SeSAME Syndrome and Beyond: The Spectrum of Kir4.1- and Kir5.1-Associated Channelopathies.Frontiers in physiology · 2022Review
- The A818-6 system as an in-vitro model for studying the role of the transportome in pancreatic cancer.BMC cancer · 2020Article
- Calcium-sensing receptor regulates intestinal dipeptide absorption via CaPhysiological reports · 2020Article
- Different functional roles for KBiology open · 2019Article
- The voltage sensing phosphatase (VSP) localizes to the apical membrane of kidney tubule epithelial cells.PloS one · 2019Article
- Article
- A mathematical model of calcium dynamics in HSY cells.PLoS computational biology · 2017Article
- Gastrointestinal transport of calcium and glucose in lactating ewes.Physiological reports · 2016Article
- Evidence of K+ channel function in epithelial cell migration, proliferation, and repair.American journal of physiology. Cell physiology · 2014Review
- A role for two-pore potassium (K2P) channels in endometrial epithelial function.Journal of cellular and molecular medicine · 2013Article
- Voltage-gated K+ channels in adipogenic differentiation of bone marrow-derived human mesenchymal stem cells.Acta pharmacologica Sinica · 2013Article
- Identification of uterine ion transporters for mineralisation precursors of the avian eggshell.BMC physiology · 2012Article
- Basolateral membrane K+ channels in renal epithelial cells.American journal of physiology. Renal physiology · 2012Review
- Differential expression of potassium channels in placentas from normal and pathological pregnancies: targeting of the K(ir) 2.1 channel to lipid rafts.The Journal of membrane biology · 2012Article
- Hydrogen sulfide: role in ion channel and transporter modulation in the eye.Frontiers in physiology · 2012Article
- K(Ca)3.1 channels facilitate K+ secretion or Na+ absorption depending on apical or basolateral P2Y receptor stimulation.The Journal of physiology · 2011Article
- Cell confluency-induced Stat3 activation regulates NHE3 expression by recruiting Sp1 and Sp3 to the proximal NHE3 promoter region during epithelial dome formation.American journal of physiology. Cell physiology · 2009Article
- Functional coupling of TRPV4 cationic channel and large conductance, calcium-dependent potassium channel in human bronchial epithelial cell lines.Pflugers Archiv : European journal of physiology · 2008Article
- Palmatine, a protoberberine alkaloid, inhibits both Ca(2+)- and cAMP-activated Cl(-) secretion in isolated rat distal colon.British journal of pharmacology · 2008Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epithelial cells in the kidney, gastrointestinal tract and exocrine glands are engaged in vectorial transport of salt and nutrients. In these tissues, K(+) channels play an important role for the stabilization of membrane voltage and maintenance of the driving force for electrogenic transport. Luminal K(+) channels represent an exit pathway for the excretion of K(+) in secreted fluid, urine and faeces, thereby effecting body K(+) homeostasis. Indeed, the expression and function of several luminal K(+) channels is modulated by hormones regulating water, Na(+), and K(+) metabolism. In addition to net transport of K(+) in the serosal (or apical) direction, K(+) channels can be coupled functionally to K(+)-transporting ATPases such as the basolateral Na(+)/K(+) ATPase or the luminal H(+)/K(+) ATPase. These ATPases export Na(+) or H(+) and take up K(+), which is then recycled via K(+) channels. This review gives a short overview on the molecular identity of epithelial K(+) channels and summarizes the different mechanisms of K(+) channel function during transport in epithelial cells.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.