ArticleInfection and immunity2003
Coordinated expression of tracheal antimicrobial peptide and inflammatory-response elements in the lungs of neonatal calves with acute bacterial pneumonia.
Article in Infection and immunity, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 51 citations in OpenAlex.
- Regulation of Paneth cell-specific genes in COVID-19 patients and SARS-CoV-2-infected mice by quantification of mRNA from exfoliated cells in stool samples.Scientific reports · 2024Article
- Individual genomic loci, transcript level, and biochemical profile of immune and antioxidant markers associated with genetically identified bacterial mastitis in Shami goats in Egypt.Open veterinary journal · 2024Article
- Individual Genomic Loci and mRNA Levels of Immune Biomarkers Associated with Pneumonia Susceptibility in Baladi Goats.Veterinary sciences · 2023Article
- Single Nucleotide Polymorphisms, Gene Expression and Economic Evaluation of Parameters Associated with Mastitis Susceptibility in European Cattle Breeds.Veterinary sciences · 2022Article
- Gut microbiome colonization and development in neonatal ruminants: Strategies, prospects, and opportunities.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2021Review
- Antimicrobial Peptides in Farm Animals: An Updated Review on Its Diversity, Function, Modes of Action and Therapeutic Prospects.Veterinary sciences · 2020Review
- The Immunology of Bovine Respiratory Disease: Recent Advancements.The Veterinary clinics of North America. Food animal practice · 2020Review
- Pulmonary and systemic responses to aerosolized lysate of Staphylococcus aureus and Escherichia coli in calves.BMC veterinary research · 2020Article
- Transcriptomics analysis of host liver and meta-transcriptome analysis of rumen epimural microbial community in young calves treated with artificial dosing of rumen content from adult donor cow.Scientific reports · 2019Article
- Article
- A Differential Innate Immune Response in Active and Chronic Stages of Bovine Infectious Digital Dermatitis.Frontiers in microbiology · 2018Article
- β-Defensins: Farming the Microbiome for Homeostasis and Health.Frontiers in immunology · 2018Review
- The human cathelicidin LL-37 inhibits influenza A viruses through a mechanism distinct from that of surfactant protein D or defensins.The Journal of general virology · 2013Article
- Reproductive tissue-specific expression profiling and genetic variation across a 19 gene bovine β-defensin cluster.Immunogenetics · 2011Article
- Different messenger RNA expression for the antimicrobial peptides beta-defensins between Meishan and crossbred pigs.Molecular biology reports · 2010Article
- Measuring antimicrobial peptide activity on epithelial surfaces in cell culture.Methods in molecular biology (Clifton, N.J.) · 2010Article
- Human defensins and LL-37 in mucosal immunity.Journal of leukocyte biology · 2010Review
- The roles of antimicrobial peptides in innate host defense.Current pharmaceutical design · 2009Review
- Effect of corticosteroids and neuropeptides on the expression of defensins in bovine tracheal epithelial cells.Infection and immunity · 2007Article
- Inhibition of beta-defensin gene expression in airway epithelial cells by low doses of residual oil fly ash is mediated by vanadium.Toxicological sciences : an official journal of the Society of Toxicology · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lung tissue removed from neonatal calves with acute Mannheimia haemolytica pneumonia showed that rapid up-regulation of the basal mRNA expression of tracheal antimicrobial peptide (TAP), NF-kappa B, and intercellular adhesion molecule 1 occurred after infection; TAP and interleukin 8 expression were highly correlated. This work suggests that the coordinated expression of beta-defensin and inflammatory elements occurs during bacterial pneumonia.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.