Evidence map›Paper›PMID 12700889›Full record

ReviewJournal of molecular medicine (Berlin, Germany)2003

Resistin: molecular history and prognosis.

Ronadip R Banerjee, Mitchell A Lazar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of molecular medicine (Berlin, Germany), 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
10.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 149 citations in OpenAlex.

  1. Gender differences in the metabolic syndrome and their role for cardiovascular disease.Clinical research in cardiology : official journal of the German Cardiac Society · 2006
    Pooled it
  2. Aging and Adiposity-Focus on Biological Females at Midlife and Beyond.International journal of molecular sciences · 2024
    Review
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  17. [Adipokine update - new molecules, new functions].Wiener medizinische Wochenschrift (1946) · 2010
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ronadip R BanerjeeDivision of Endocrinology, Diabetes, and Metabolism, Penn Diabetes Center, University of Pennsylvania School of Medicine, 415 Curie Blvd., Philadelphia, PA 19104-6149, USA.
Mitchell A Lazar
University of Pennsylvania · US

Funding

VIRAL VECTOR COREP30DK019525 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI MITCHELL A. LAZAR · 1986 to 2026
$48.3M
ZINC FINGER PROTEINS IN EARLY KIDNEY DEVELOPMENTP01DK049210 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI AHIMA, REXFORD S. · 1995 to 2016
$26.9M
Nuclear Receptors in Metabolic TissuesR01DK049780 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI LAZAR, MITCHELL A. · 1995 to 2025
$10.8M
NIDDK NIH HHS DK19525NIDDK NIH HHS DK49210NIDDK NIH HHS DK49780
6 · The paper itself

Abstract

Obesity and diabetes have reached epidemic proportions worldwide. The antidiabetic thiazolidinedione (TZD) drugs are insulin-sensitizing agents now widely used in the treatment of type 2 diabetes. TZDs are ligands for the nuclear hormone receptor peroxisome proliferator activated receptor gamma, which is a master regulator of adipogenesis and adipocyte metabolism. The molecular mechanisms by which TZDs improve insulin sensitivity have not been fully identified. Here we consider a novel secreted factor first identified as a TZD-suppressible gene in mouse adipocytes, called resistin, and discuss what is currently known about resistin regulation and function in mouse and human.

Indexed as

Intercellular Signaling Peptides and ProteinsProteinsAmino Acid SequenceAnimalsGene Expression RegulationGlucocorticoidsGlucoseHormones, EctopicHypoglycemic AgentsInsulinLigandsMiceMolecular Sequence DataNerve Growth FactorNIH 3T3 CellsObesity2,4-thiazolidinedioneGlucocorticoidsGlucoseHormones, EctopicHypoglycemic AgentsInsulinIntercellular Signaling Peptides and ProteinsLigandsNerve Growth FactorProteinsResistinRetnla protein, mouseRETNLB protein, humanRetn protein, mouseThiazolidinediones

Identifiers

PMID12700889
OpenAlexW2104084470

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.