ArticleProceedings of the National Academy of Sciences of the United States of America2003
A 1-Mb resolution radiation hybrid map of the canine genome.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 74 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
74 citing papers in PubMed.
- A comprehensive review of genomic perspectives of canine diseases as a model to study human disorders.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2023Review
- Relationship of microsatellite instability to mismatch repair deficiency in malignant tumors of dogs.Journal of veterinary internal medicine · 2022Article
- Genetic diversity and mate selection in a reintroduced population of gray wolves.Scientific reports · 2022Article
- Article
- Article
- Geographic patterns in morphometric and genetic variation for coyote populations with emphasis on southeastern coyotes.Ecology and evolution · 2019Article
- Demographic history influences spatial patterns of genetic diversityin recently expanded coyote (Canis latrans) populations.Heredity · 2018Article
- New insights into the genetic composition and phylogenetic relationship of wolves and dogs in the Iberian Peninsula.Ecology and evolution · 2017Article
- A new physical mapping approach refines the sex-determining gene positions on the Silene latifolia Y-chromosome.Scientific reports · 2016Article
- Microsatellite polymorphism and its association with body weight and selected morphometrics of farm red fox (Vulpes vulpes L.).Journal of applied genetics · 2014Article
- Population genetic structure of gray wolves (Canis lupus) in a marine archipelago suggests island-mainland differentiation consistent with dietary niche.BMC ecology · 2014Article
- Genetic structure, spatial organization, and dispersal in two populations of bat-eared foxes.Ecology and evolution · 2013Article
- Article
- The genetics of canine skull shape variation.Genetics · 2013Article
- Genetics of behavior in the silver fox.Mammalian genome : official journal of the International Mammalian Genome Society · 2012Review
- Genetic and phenotypic variations of inherited retinal diseases in dogs: the power of within- and across-breed studies.Mammalian genome : official journal of the International Mammalian Genome Society · 2012Review
- Annotation of the domestic dog genome sequence: finding the missing genes.Mammalian genome : official journal of the International Mammalian Genome Society · 2012Article
- Genomic sweep and potential genetic rescue during limiting environmental conditions in an isolated wolf population.Proceedings. Biological sciences · 2011Article
- A one base pair deletion in the canine ATP13A2 gene causes exon skipping and late-onset neuronal ceroid lipofuscinosis in the Tibetan terrier.PLoS genetics · 2011Article
- The domestic dog: man's best friend in the genomic era.Genome biology · 2011Review
14 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
Abstract
The purebred dog population consists of >300 partially inbred genetic isolates or breeds. Restriction of gene flow between breeds, together with strong selection for traits, has led to the establishment of a unique resource for dissecting the genetic basis of simple and complex mammalian traits. Toward this end, we present a comprehensive radiation hybrid map of the canine genome composed of 3,270 markers including 1,596 microsatellite-based markers, 900 cloned gene sequences and ESTs, 668 canine-specific bacterial artificial chromosome (BAC) ends, and 106 sequence-tagged sites. The map was constructed by using the RHDF5000-2 whole-genome radiation hybrid panel and computed by using MULTIMAP and TSP/CONCORDE. The 3,270 markers map to 3,021 unique positions and define an average intermarker distance corresponding to 1 Mb. We also define a minimal screening set of 325 highly informative well spaced markers, to be used in the initiation of genome-wide scans. The well defined synteny between the dog and human genomes, established in part as a function of this work by the identification of 85 conserved fragments, will allow follow-up of initial findings of linkage by selection of candidate genes from the human genome sequence. This work continues to define the canine system as the method of choice in the pursuit of the genes causing mammalian variation and disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.