Evidence map›Paper›PMID 12697454›Full record

ReviewTrends in immunology2003

Adaptive immune response of Vgamma2Vdelta2 T cells: a new paradigm.

Zheng W Chen, Norman L Letvin

Abstract readReview
In one paragraph

Review in Trends in immunology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zheng W ChenTuberculosis Research Unit, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, RE113/RE216, Boston, MA 02115, USA. zchen@caregroup.harvard.edu
Norman L Letvin

Funding

MODEL OF AIDS VIRUS-RELATED PULMONARY TUBERCULOSISR01HL064560 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHEN, ZHENG W · 1999 to 2014
$9.5M
SIV/MYCOBACTERIUM COINFECTIONR01RR013601 · NCRR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI CHEN, ZHENG W · 1998 to 2008
$4.4M
NCRR NIH HHS R01 RR013601NCRR NIH HHS RR 13601NHLBI NIH HHS HL 64560NHLBI NIH HHS R01 HL064560
6 · The paper itself

Abstract

The role of gammadelta T cells in adaptive immunity remains uncertain. Recent studies have demonstrated that a unique subset of gammadelta T cells in primates can mount adaptive immune responses during mycobacterial infections. This Review discusses notable similarities and differences in adaptive immune responses between non-peptide-specific gammadelta T cells and peptide-specific alphabeta T cells, and discusses both the molecular basis for gammadelta T-cell responses and potential functions of these enigmatic cells.

Indexed as

AnimalsCell MovementGenes, T-Cell ReceptorHumansMycobacterium bovisPrimatesReceptors, Antigen, T-Cell, gamma-deltaT-LymphocytesReceptors, Antigen, T-Cell, gamma-delta

Identifiers

PMID12697454
PMCPMC2869283

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.