ArticleNeuroradiology2003
Perfusion MRI in the evaluation of the relationship between tumour growth, necrosis and angiogenesis in glioblastomas and grade 1 meningiomas.
Article in Neuroradiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 34 citations in OpenAlex.
- Article
- In vivo quantification of mandibular bone remodeling and vascular changes in a Wistar rat model: A novel HR-MRI and micro-CT fusion technique.Imaging science in dentistry · 2020Article
- Intraoperative Contrast Enhanced Ultrasound Evaluates the Grade of Glioma.BioMed research international · 2016Article
- Survival analysis of patients with high-grade gliomas based on data mining of imaging variables.AJNR. American journal of neuroradiology · 2012Article
- Clinical characteristics of meningiomas assessed by ¹¹C-methionine and ¹⁸F-fluorodeoxyglucose positron-emission tomography.Journal of neuro-oncology · 2012Article
- Stripe-like increase of rCBV beyond the visible border of glioblastomas: site of tumor infiltration growing after neurosurgery.Journal of neuro-oncology · 2011Article
- The striate sign: peritumoural perfusion pattern of infiltrative primary and recurrent gliomas.Neurosurgical review · 2010Article
- Role of perfusion-weighted imaging at 3 Tesla in the assessment of malignancy of cerebral gliomas.La Radiologia medica · 2008Article
- Comparison of first-pass and second-bolus dynamic susceptibility perfusion MRI in brain tumors.Neuroradiology · 2006Article
- Meningiomas with conventional MRI findings resembling intraaxial tumors: can perfusion-weighted MRI be helpful in differentiation?Neuroradiology · 2006Article
- Malignancy-associated vessel tortuosity: a computer-assisted, MR angiographic study of choroid plexus carcinoma in genetically engineered mice.AJNR. American journal of neuroradiology · 2006Article
- Follow-up gliomas after radiotherapy: 1H MR spectroscopic imaging for increasing diagnostic accuracy.Neuroradiology · 2005Article
- Magnetic resonance angiography visualization of abnormal tumor vasculature in genetically engineered mice.Cancer research · 2005Article
- Imaging-based observational databases for clinical problem solving: the role of informatics.Journal of the American Medical Informatics Association : JAMIAArticle
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Angiogenesis is a common characteristic of tumours, and it is reasonable to assume that it has an influence on tumour growth, depending on the grade of malignancy. We therefore studied angiogenesis in 25 patients: 14 with glioblastoma multiforme and 11 with grade I meningioma. Our aim was to assess how angiogenesis conditions growth and necrosis. The patients underwent MRI with standard and perfusion sequences. We calculated the volume of each tumour; for the glioblastomas the solid portion was taken as the difference between the overall volume and the volume of any necrotic portion. In the glioblastomas, we found an inverse relationship between blood volume and the size of the tumour, whereas in the meningiomas there was of a direct relationship. These correlations confirm in vivo the knowledge about necrosis in glioblastomas and its relationship to their inadequate vascular network. On the contrary, grade 1 meningiomas show an equilibrium between their microcirculation and the cellular component.
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