ArticleMolecular biology of the cell2003
A kinesin mutant with an atypical bipolar spindle undergoes normal mitosis.
Article in Molecular biology of the cell, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 76 citations in OpenAlex.
- KATANIN promotes cell elongation and division to generate proper cell numbers in maize organs.Nature communications · 2026Article
- Mutation of OsKIF14.3, a Kinesin-14 Subfamily Protein, Altered Starch Metabolism and Caused Yellowish Leaf in Rice.International journal of molecular sciences · 2025Article
- The unconventional TPX2 family protein TPXL3 regulates α Aurora kinase function in spindle morphogenesis in Arabidopsis.The Plant cell · 2025Article
- A combined transcriptome - miRNAome approach revealed that aFrontiers in plant science · 2022Article
- Two Kinesin-14A Motors Oligomerize to Drive Poleward Microtubule Convergence for Acentrosomal Spindle Morphogenesis inFrontiers in cell and developmental biology · 2022Article
- Optimal BR signalling is required for adequate cell wall orientation in the Arabidopsis root meristem.Development (Cambridge, England) · 2021Article
- A malectin domain kinesin functions in pollen and seed development in Arabidopsis.Journal of experimental botany · 2020Article
- Maize VKS1 Regulates Mitosis and Cytokinesis During Early Endosperm Development.The Plant cell · 2019Article
- Kinesins and Myosins: Molecular Motors that Coordinate Cellular Functions in Plants.Annual review of plant biology · 2018Review
- The preprophase band-associated kinesin-14 OsKCH2 is a processive minus-end-directed microtubule motor.Nature communications · 2018Article
- A rice class-XIV kinesin enters the nucleus in response to cold.Scientific reports · 2018Article
- Review
- The mitotic kinesin-14 KlpA contains a context-dependent directionality switch.Nature communications · 2017Article
- Shared characteristics underpinning C4 leaf maturation derived from analysis of multiple C3 and C4 species of Flaveria.Journal of experimental botany · 2017Article
- Microtubules contribute to tubule elongation and anchoring of endoplasmic reticulum, resulting in high network complexity in Arabidopsis.Plant physiology · 2014Article
- The Arabidopsis kinesin gene AtKin-1 plays a role in the nuclear division process during megagametogenesis.Plant cell reports · 2014Article
- MAPs: cellular navigators for microtubule array orientations in Arabidopsis.Plant cell reports · 2014Review
- Functions of the Arabidopsis kinesin superfamily of microtubule-based motor proteins.Protoplasma · 2012Review
- The novel functions of kinesin motor proteins in plants.Protoplasma · 2012Review
- Potential roles for Kinesins at the cortical division site.Frontiers in plant science · 2012Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Motor proteins have been implicated in various aspects of mitosis, including spindle assembly and chromosome segregation. Here, we show that acentrosomal Arabidopsis cells that are mutant for the kinesin, ATK1, lack microtubule accumulation at the predicted spindle poles during prophase and have reduced spindle bipolarity during prometaphase. Nonetheless, all abnormalities are rectified by anaphase and chromosome segregation appears normal. We conclude that ATK1 is required for normal microtubule accumulation at the spindle poles during prophase and possibly functions in spindle assembly during prometaphase. Because aberrant spindle morphology in these mutants is resolved by anaphase, we postulate that mitotic plant cells contain an error-correcting mechanism. Moreover, ATK1 function seems to be dosage-dependent, because cells containing one wild-type allele take significantly longer to proceed to anaphase as compared with cells containing two wild-type alleles.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.