ReviewCurrent psychiatry reports2003
Linkage and association studies of schizophrenia.
Review in Current psychiatry reports, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Cognitive reserve and its correlates in child and adolescent offspring of patients diagnosed with schizophrenia or bipolar disorder.European child & adolescent psychiatry · 2023Article
- Relationship betweenIranian journal of public health · 2021Article
- Psychosocial Stress Induces Schizophrenia-Like Behavior in Mice With Reduced MMP-9 Activity.Frontiers in behavioral neuroscience · 2019Article
- TCF4 and GRM8 gene polymorphisms and risk of schizophrenia in an Iranian population: a case-control study.Molecular biology reports · 2018Article
- Drug Abuse and Psychosis: New Insights into Drug-induced Psychosis.Experimental neurobiology · 2017Review
- Expression of the G72/G30 gene in transgenic mice induces behavioral changes.Molecular psychiatry · 2014Article
- Article
- Association mapping of quantitative disease resistance in a natural population of loblolly pine (Pinus taeda L.).Genetics · 2010Article
- Article
- Lack of association between the -839C/T polymorphism in the SLC6A3 gene promoter and schizophrenia in the Iranian population.Journal of genetics · 2009Article
- Association between the G1001C polymorphism in the GRIN1 gene promoter and schizophrenia in the Iranian population.Journal of molecular neuroscience : MN · 2009Article
- Conference report--highlights of the 4th EMBO/EMBL joint conference on genetics, determinism and human freedom, November 14-15, 2003; Heidelberg, Germany.MedGenMed : Medscape general medicine · 2004Article
- Molecular genetics of schizophrenia: a critical review.Journal of psychiatry & neuroscience : JPN · 2003Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recent twin studies confirm that schizophrenia is highly heritable, but attempts to locate and identify genes have proved to be difficult. This is largely because major genes appear to be rare or nonexistent. Instead, genetic liability almost certainly results from the combined effects of multiple susceptibility loci and most studies have been under-equipped to detect such effects. Nevertheless, several regions of the genome have been implicated by more than one linkage study and chromosome 22q has been implicated by linkage and by studies of patients with microdeletions. Recent work attempting to refine regions of interest using linkage dysequilibrium mapping has identified four promising and novel "positional candidates;" they are neuregulin-1 on chromosome 8p-p21, G72 located at chromosome 13q34, dysbindin at 6p22.3, and proline dehydrogenase, which is a gene that maps to chromosome 22q11. In addition, there is renewed interest in a fifth gene, catechol-O-methyltransferase, also on chromosome 22q11.
Indexed as
Identifiers
12685991What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.