Evidence map›Paper›PMID 12680695›Full record

ArticleVirus genes2003

Snow Mountain virus genome sequence and virus-like particle assembly.

Vance P Lochridge, Michele E Hardy

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Virus genes, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
  2. Journal of structural biology: X · 2020
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Intergenogroup recombination in sapoviruses.Emerging infectious diseases · 2005
    Article
  14. Genetic diversity and recombination of porcine sapoviruses.Journal of clinical microbiology · 2005
    Article
  15. Porcine noroviruses related to human noroviruses.Emerging infectious diseases · 2005
    Article
  16. Characterization of new recombinant noroviruses.Journal of clinical microbiology · 2005
    Article
  17. Article
  18. Article
  19. Article
  20. Virus-like particles: models for assembly studies and foreign epitope carriers.Progress in nucleic acid research and molecular biology · 2005
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Vance P LochridgeVeterinary Molecular Biology Laboratory, PO Box 173610, Montana State University, Bozeman, MT 59717-3610, USA.
Michele E Hardy
Montana State University · US

Funding

MOLECULAR MECHANISMS OF NORWALK VIRUS GENOME EXPRESSIONR01AI043450 · NIAID · MONTANA STATE UNIVERSITY (BOZEMAN) · PI HARDY, MICHELE E · 1999 to 2003
$550k
NIAID NIH HHS AI-43450
6 · The paper itself

Abstract

Snow Mountain virus (SMV) belongs to the Norovirus genus of the Caliciviridae family. SMV is a genogroup II (GII) reference strain of human enteric caliciviruses associated with epidemic gastroenteritis. In this study, the positive sense RNA genome sequence of SMV was determined to be 7,537 nucleotides in length excluding the 3' polyadenylated tract. The genome is organized into three open reading frames typical of caliciviruses in the Norovirus genus. Pairwise sequence alignments showed SMV ORF1 is highly conserved with other genogroup II noroviruses, and most closely related to GII strains Melksham and Hawaii virus. In addition, comparative sequence analyses indicated that SMV is likely a recombinant norovirus. VP1/VP2 proteins self-assembled into virus-like particles (VLPs) when expressed in insect cells by a recombinant baculovirus. Characterization of one clone that expressed VP1, but failed to assemble into VLPs, identified histidine residue 91 as important for particle assembly under standard conditions of expression.

Indexed as

Genome, ViralCaliciviridaeCaliciviridae InfectionsCapsid ProteinsDNA, ComplementaryFecesGastroenteritisHumansMolecular Sequence DataMorphogenesisNucleopolyhedrovirusesOpen Reading FramesRecombinant Fusion ProteinsRNA, ViralSequence AlignmentSequence Homology, Nucleic AcidCapsid ProteinsDNA, ComplementaryRecombinant Fusion ProteinsRNA, Viral

Identifiers

PMID12680695
OpenAlexW146748877

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.