SynthesisBMJ (Clinical research ed.)2003
Prevalence of Helicobacter pylori in patients with gastro-oesophageal reflux disease: systematic review.
Synthesis in BMJ (Clinical research ed.), 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 88 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
88 citing papers in PubMed, 3 syntheses or guidelines pooled it, 330 citations in OpenAlex.
- Association Between Helicobacter pylori Exposure and Decreased Odds of Eosinophilic Esophagitis-A Systematic Review and Meta-analysis.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2019Pooled it
- Pooled it
- Helicobacter pylori eradication for Parkinson's disease.The Cochrane database of systematic reviews · 2011Pooled it
- Acid-suppression therapy offers varied laryngopharyngeal and esophageal symptom relief in laryngopharyngeal reflux patients.Digestive diseases and sciences · 2008Trial
- Helicobacter pylori eradication versus prokinetics in the treatment of functional dyspepsia: a randomized, double-blind study.Journal of gastroenterology · 2006Trial
- Clinical features of gastroesophageal reflux disease and erosive esophagitis: Insights from patients undergoing esophagogastroduodenoscopy in resource-limited Ethiopia.World journal of gastroenterology · 2024Article
- Article
- Relationship between nonrestorative sleep and heartburn among a Japanese occupational population.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2023Article
- Prevalence of Helicobacter pylori Infection in Bariatric Surgery Patients.Obesity surgery · 2023Article
- Disease trends afterWorld journal of gastroenterology · 2023Article
- Review
- Inverse relations betweenWorld journal of gastrointestinal oncology · 2022Article
- Inverse correlation between gastroesophageal reflux disease and atrophic gastritis assessed by endoscopy and serology.World journal of gastroenterology · 2022Article
- Management of Helicobacter pylori infection: The Bhubaneswar Consensus Report of the Indian Society of Gastroenterology.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2021Article
- Evaluations of Gastric Acid Pocket Using Novel Vertical 8-Channel pH Monitoring System and Effects of Acid Secretion Inhibitors.Journal of neurogastroenterology and motility · 2021Article
- Risk of Reflux-Related Symptoms and Reflux Esophagitis afterJournal of clinical medicine · 2021Article
- Advanced Endoscopic Imaging and Interventions in GERD: An Update and Future Directions.Frontiers in medicine · 2021Review
- Endoscopic Reflux Esophagitis and Reflux-Related Symptoms afterJournal of clinical medicine · 2020Article
- Association of Helicobacter pylori infection with gastroesophageal reflux disease.The Journal of international medical research · 2019Article
- IS THERE A RELATION BETWEEN HELYBACTER PYLORI AND INTESTINAL METAPLASIA IN SHORT COLUMN EPITELIZATION UP TO 10 MM IN THE DISTAL ESOPHAGUS?Arquivos brasileiros de cirurgia digestiva : ABCD = Brazilian archives of digestive surgery · 2019Article
28 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo ascertain the prevalence of Helicobacter pylori in patients with gastro-oesophageal reflux disease and its association with the disease.
designSystematic review of studies reporting the prevalence of H pylori in patients with and without gastro-oesophageal reflux disease. DATA SOURCES: Four electronic databases, searched to November 2001, experts, pharmaceutical companies, and journals.
main outcome measureOdds ratio for prevalence of H pylori in patients with gastro-oesophageal reflux disease.
results20 studies were included. The pooled estimate of the odds ratio for prevalence of H pylori was 0.60 (95% confidence interval 0.47 to 0.78), indicating a lower prevalence in patients with gastro-oesophageal reflux disease. Substantial heterogeneity was observed between studies. Location seemed to be an important factor, with a much lower prevalence of H pylori in patients with gastro-oesophageal reflux disease in studies from the Far East, despite a higher overall prevalence of infection than western Europe and North America. Year of study was not a source of heterogeneity.
conclusionThe prevalence of H pylori infection was significantly lower in patients with than without gastro-oesophageal reflux, with geographical location being a strong contributor to the heterogeneity between studies. Patients from the Far East with reflux disease had a lower prevalence of H pylori infection than patients from western Europe and North America, despite a higher prevalence in the general population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.