ArticleApplied and environmental microbiology2003
Production of diarrheal enterotoxins and other potential virulence factors by veterinary isolates of bacillus species associated with nongastrointestinal infections.
Article in Applied and environmental microbiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 89 citations in OpenAlex.
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- Toxigenic diversity ofFood science and biotechnology · 2024Article
- A buffalo rumen-derived probiotic (SN-6) could effectively increase simmental growth performance by regulating fecal microbiota and metabolism.Frontiers in microbiology · 2022Article
- Safety and Stability Assessment of Potential Probiotic Strains from Fermented Mango Brine Pickle.Probiotics and antimicrobial proteins · 2020Article
- Microbial survey of ready-to-eat salad ingredients sold at retail reveals the occurrence and the persistence of Listeria monocytogenes Sequence Types 2 and 87 in pre-packed smoked salmon.BMC microbiology · 2017Article
- The genetic diversity of cereulide biosynthesis gene cluster indicates a composite transposon Tnces in emetic Bacillus weihenstephanensis.BMC microbiology · 2014Article
- Public health implications of contamination of Franc CFA (XAF) circulating in Buea (Cameroon) with drug resistant pathogens.BMC research notes · 2014Article
- Biotoxin detection using cell-based sensors.Toxins · 2013Review
- Probiotic Activity of a Bacterial Strain Isolated from Ancient Permafrost Against Salmonella Infection in Mice.Probiotics and antimicrobial proteins · 2012Article
- Phenotypic & genetic characterization of Bacillus cereus isolated from the acute diarrhoeal patients.The Indian journal of medical research · 2011Article
- InhA1, NprA, and HlyII as candidates for markers to differentiate pathogenic from nonpathogenic Bacillus cereus strains.Journal of clinical microbiology · 2010Article
- Monitoring growth phase-related changes in phosphatidylcholine-specific phospholipase C production, adhesion properties and physiology of Bacillus cereus vegetative cells.Journal of industrial microbiology & biotechnology · 2008Article
- The safety of two Bacillus probiotic strains for human use.Digestive diseases and sciences · 2008Article
- Rapid Ped-2E9 cell-based cytotoxicity analysis and genotyping of Bacillus species.Journal of clinical microbiology · 2005Article
- Toxin-producing ability among Bacillus spp. outside the Bacillus cereus group.Applied and environmental microbiology · 2005Article
- Identification and partial characterization of the nonribosomal peptide synthetase gene responsible for cereulide production in emetic Bacillus cereus.Applied and environmental microbiology · 2005Article
- Genotyping and toxigenic potential of Bacillus subtilis and Bacillus pumilus strains occurring in industrial and artisanal cured sausages.Applied and environmental microbiology · 2004Article
- Identification of anthrax toxin genes in a Bacillus cereus associated with an illness resembling inhalation anthrax.Proceedings of the National Academy of Sciences of the United States of America · 2004Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
With the exceptions of Bacillus cereus and Bacillus anthracis, Bacillus species are generally perceived to be inconsequential. However, the relevance of other Bacillus species as food poisoning organisms and etiological agents in nongastrointestinal infections is being increasingly recognized. Eleven Bacillus species isolated from veterinary samples associated with severe nongastrointestinal infections were assessed for the presence and expression of diarrheagenic enterotoxins and other potential virulence factors. PCR studies revealed the presence of DNA sequences encoding hemolysin BL (HBL) enterotoxin complex and B. cereus enterotoxin T (BceT) in five B. cereus strains and in Bacillus coagulans NB11. Enterotoxin HBL was also harbored by Bacillus polymyxa NB6. After 18 h of growth in brain heart infusion broth, all seven Bacillus isolates carrying genes encoding enterotoxin HBL produced this toxin. Cell-free supernatant fluids from all 11 Bacillus isolates demonstrated cytotoxicity toward human HEp-2 cells; only one Bacillus licheniformis strain adhered to this test cell line, and none of the Bacillus isolates were invasive. This study constitutes the first demonstration that Bacillus spp. associated with serious nongastrointestinal infections in animals may harbor and express diarrheagenic enterotoxins traditionally linked to toxigenic B. cereus.
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