ArticleThe Plant cell2003
Alternative splicing modulation by a LAMMER kinase impinges on developmental and transcriptome expression.
Article in The Plant cell, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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Who cites it
38 citing papers in PubMed, 74 citations in OpenAlex.
- Role of the LAMMER kinase LkhA in fungal development and aflatoxin production in Aspergillus flavus.Journal of microbiology (Seoul, Korea) · 2025Article
- Genome-Scale Identification of Wild Soybean Serine/Arginine-Rich Protein Family Genes and Their Responses to Abiotic Stresses.International journal of molecular sciences · 2024Article
- LAMMER Kinase Governs the Expression and Cellular Localization of Gas2, a Key Regulator of Flocculation in Schizosaccharomyces pombe.Journal of microbiology (Seoul, Korea) · 2024Article
- Pleiotropic roles of LAMMER kinase, Lkh1 in stress responses and virulence ofFrontiers in cellular and infection microbiology · 2024Article
- Review
- Relevance and Regulation of Alternative Splicing in Plant Heat Stress Response: Current Understanding and Future Directions.Frontiers in plant science · 2022Review
- The LAMMER Kinase, LkhA, AffectsFrontiers in cellular and infection microbiology · 2021Article
- Transcriptome Analysis of Alternative Splicing Events Induced by Arbuscular Mycorrhizal Fungi (Plants (Basel, Switzerland) · 2020Article
- Genome-wide association analysis of stalk biomass and anatomical traits in maize.BMC plant biology · 2019Article
- The Dual-Specificity LAMMER Kinase Affects Stress-Response and Morphological Plasticity in Fungi.Frontiers in cellular and infection microbiology · 2019Review
- Rapid and Dynamic Alternative Splicing Impacts the Arabidopsis Cold Response Transcriptome.The Plant cell · 2018Article
- Two Different Transcripts of a LAMMER Kinase Gene Play Opposite Roles in Disease Resistance.Plant physiology · 2016Article
- Pre-mRNA Splicing in Plants: In Vivo Functions of RNA-Binding Proteins Implicated in the Splicing Process.Biomolecules · 2015Review
- Splicing of receptor-like kinase-encoding SNC4 and CERK1 is regulated by two conserved splicing factors that are required for plant immunity.Molecular plant · 2014Article
- Multifunctional RNA processing protein SRm160 induces apoptosis and regulates eye and genital development in Drosophila.Genetics · 2014Article
- Genome-wide survey of cold stress regulated alternative splicing in Arabidopsis thaliana with tiling microarray.PloS one · 2013Article
- An hnRNP-like RNA-binding protein affects alternative splicing by in vivo interaction with transcripts in Arabidopsis thaliana.Nucleic acids research · 2012Article
- Alternative splicing in plants--coming of age.Trends in plant science · 2012Review
- Transcriptome survey reveals increased complexity of the alternative splicing landscape in Arabidopsis.Genome research · 2012Article
- Localization and dynamics of nuclear speckles in plants.Plant physiology · 2012Review
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alternative splicing is a major contributor to genome complexity, playing a significant role in various cellular functions, including signal transduction, immunity, and development. The spliceosomal machinery is responsible for the processing of nuclear RNA. Several splicing factors associated with this complex are phosphorylated by kinases that possess a conserved LAMMER motif. We demonstrate in BY-2 tobacco cells a novel role for the LAMMER motif in the maintenance of proper subnuclear localization. Furthermore, high expression of the LAMMER kinase in Arabidopsis plants modulated the alternative splicing of specific endogenous genes and resulted in abnormal plant development and a novel transcriptome profile. A prominent feature was the upregulation of genes that play a role in protein turnover, suggesting a moderating function for these gene products in the control of alternative splicing events. Together, these results demonstrate alternative splicing modulation as a result of phosphorylation activity, providing an opportunity to study its global effect on the plasticity of plant development and gene expression at the organism level.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.