ArticleProceedings of the National Academy of Sciences of the United States of America2003
The Arabidopsis outward K+ channel GORK is involved in regulation of stomatal movements and plant transpiration.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 162 papers, 1 of them a synthesis that pooled it.
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Who cites it
162 citing papers in PubMed, 1 synthesis or guideline pooled it, 426 citations in OpenAlex.
- Revisiting the relationship between stomatal size and speed across species - a meta-analysis.The New phytologist · 2026Pooled it
- AKT5 is a bona fide potassium channel and controls petiole growth inScience advances · 2026Article
- COJournal of integrative plant biology · 2026Article
- Concurrent Temperature and Light Intensity Fluctuations Promote Stomatal Opening and Non-Steady State Photosynthesis.Plant, cell & environment · 2026Article
- A Salt-ResponsiveInternational journal of molecular sciences · 2026Article
- Genomic Regions Associated with Drought Tolerance and Other Traits in Lentils (Plants (Basel, Switzerland) · 2026Article
- OsKAT1 is a short Shaker potassium channel involved in root-to-shoot potassium translocation and contributes to rice grain yield.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Bioorganic studies on the nyctinastic leaf-movement of plants.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2026Review
- Regulation of vacuole fusion in stomata by dephosphorylation of the HOPS subunit VPS39.The Plant journal : for cell and molecular biology · 2025Article
- Structural and mechanistic insights into symmetry conversion in plant GORK K+ channel regulation.Protein & cell · 2025Article
- Multi-omics exploration of the involvement of ABA in identifying unique molecular markers for single and combined stresses in tomato plants.Journal of experimental botany · 2025Article
- Structure reveals a regulation mechanism of plant outward-rectifying KProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Identification and evaluation of low-pH-tolerant Cheongcheong/Nagdong-double haploid rice lines via QTL analysis.BMC plant biology · 2025Article
- The Arabidopsis F-box protein FBS associated with the helix-loop-helix transcription factor FAMA involved in stomatal immunity.Plant molecular biology · 2025Article
- GORK KNature communications · 2025Article
- A C4 plant K+ channel accelerates stomata to enhance C3 photosynthesis and water use efficiency.Plant physiology · 2025Article
- Chloride transport and homeostasis in plants.Quantitative plant biology · 2025Review
- Potassium extrusion by plant cells: evolution from an emergency valve to a driver of long-distance transport.The New phytologist · 2025Review
- Elucidating the downstream pathways triggered by HPlant signaling & behavior · 2024Article
- Fast stomatal kinetics in sorghum enable tight coordination with photosynthetic responses to dynamic light intensity and safeguard high water use efficiency.Journal of experimental botany · 2024Article
102 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
13 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microscopic pores present in the epidermis of plant aerial organs, called stomata, allow gas exchanges between the inner photosynthetic tissue and the atmosphere. Regulation of stomatal aperture, preventing excess transpirational vapor loss, relies on turgor changes of two highly differentiated epidermal cells surrounding the pore, the guard cells. Increased guard cell turgor due to increased solute accumulation results in stomatal opening, whereas decreased guard cell turgor due to decreased solute accumulation results in stomatal closing. Here we provide direct evidence, based on reverse genetics approaches, that the Arabidopsis GORK Shaker gene encodes the major voltage-gated outwardly rectifying K(+) channel of the guard cell membrane. Expression of GORK dominant negative mutant polypeptides in transgenic Arabidopsis was found to strongly reduce outwardly rectifying K(+) channel activity in the guard cell membrane, and disruption of the GORK gene (T-DNA insertion knockout mutant) fully suppressed this activity. Bioassays on epidermal peels revealed that disruption of GORK activity resulted in impaired stomatal closure in response to darkness or the stress hormone abscisic acid [corrected]. Transpiration measurements on excised rosettes and intact plants (grown in hydroponic conditions or submitted to water stress) revealed that absence of GORK activity resulted in increased water consumption. The whole set of data indicates that GORK is likely to play a crucial role in adaptation to drought in fluctuating environments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.