ArticleJournal of bacteriology2003
Hydrogen-oxidizing capabilities of Helicobacter hepaticus and in vivo availability of the substrate.
Article in Journal of bacteriology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 35 citations in OpenAlex.
- Molecular mechanisms associated with effects of hydrogen molecule in liver diseases: the review of current evidence.European journal of medical research · 2025Review
- Molecular Hydrogen Metabolism: a Widespread Trait of Pathogenic Bacteria and Protists.Microbiology and molecular biology reviews : MMBR · 2020Review
- Site-directed mutagenesis of Campylobacter concisus respiratory genes provides insight into the pathogen's growth requirements.Scientific reports · 2018Article
- The NiFe Hydrogenases of the Tetrachloroethene-Respiring EpsilonproteobacteriumFrontiers in microbiology · 2017Article
- Roles of H2 uptake hydrogenases in Shigella flexneri acid tolerance.Microbiology (Reading, England) · 2012Article
- Characterization of a Helicobacter hepaticus putA mutant strain in host colonization and oxidative stress.Infection and immunity · 2008Article
- Deep-sea vent epsilon-proteobacterial genomes provide insights into emergence of pathogens.Proceedings of the National Academy of Sciences of the United States of America · 2007Article
- Metal-responsive gene regulation and metal transport in Helicobacter species.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2007Review
- The complete genome sequence and comparative genome analysis of the high pathogenicity Yersinia enterocolitica strain 8081.PLoS genetics · 2006Article
- Helicobacter hepaticus hydrogenase mutants are deficient in hydrogen-supported amino acid uptake and in causing liver lesions in A/J mice.Infection and immunity · 2005Article
- Respiratory hydrogen use by Salmonella enterica serovar Typhimurium is essential for virulence.Infection and immunity · 2004Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hydrogen-oxidizing hydrogenase activity was detected in Helicobacter hepaticus and compared to the activity in Helicobacter pylori for characteristics associated with hydrogen uptake respiratory hydrogenases. Intact whole cells could couple H(2) oxidation to oxygen uptake, and no H(2) uptake was observed without oxygen available to complete the respiratory pathway. The H. hepaticus enzyme coupled H(2) oxidation to reduction of many positive potential acceptors, and it underwent anaerobic or reductive activation. H. hepaticus had a strong affinity for molecular H(2) (apparent K(m) of 2.5 micro M), and microelectrode measurements on the livers of live mice demonstrated that H(2) is available in the host tissue at levels 20-fold greater than the apparent whole-cell K(m) value.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.