Evidence map›Paper›PMID 12669021›Full record

ReviewNature reviews. Immunology2003

Immune functions encoded by the natural killer gene complex.

Wayne M Yokoyama, Beatrice F M Plougastel

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Immunology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 224 papers.

0numbers the graph read from it
0cells of the map it votes in
224citing papers in PubMed
13.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

224 citing papers in PubMed, 558 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Role of Innate Immunity in Cancer.Advances in experimental medicine and biology · 2025
    Review
  11. Review
  12. Article
  13. Article
  14. Oncolytic vaccinia virus harboringMolecular therapy. Oncology · 2024
    Article
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article

164 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Wayne M YokoyamaHoward Hughes Medical Institute, Rheumatology Division, Department of Medicine, Barnes-Jewish Hospital and Washington University School of Medicine, Box 8045, 660 South Euclid Avenue, St Louis, Missouri 63110, USA. yokoyama@imgate.wustl.edu
Beatrice F M Plougastel
Barnes-Jewish Hospital · USWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There has been marked progress in our understanding of the role of natural killer (NK) cells in immune responses, mainly due to the identification of NK-cell receptors and their ligands. The genes encoding many NK-cell receptors are located in the NK-gene complex (NKC). Here, we review the properties of NKC-encoded receptors, and provide a genomic and conceptual framework for an insight into NK-cell function and biology.

Indexed as

Multigene FamilyAmino Acid SequenceAnimalsEvolution, MolecularHumansKiller Cells, NaturalLigandsMiceModels, ImmunologicalMolecular Sequence DataNeoplasmsPolymorphism, GeneticReceptors, ImmunologicSequence Homology, Amino AcidT-LymphocytesVirus DiseasesLigandsReceptors, Immunologic

Identifiers

PMID12669021
OpenAlexW2042728577

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.