Evidence map›Paper›PMID 12668902›Full record

ReviewMolecular neurobiology2003

Mammalian neural stem-cell renewal: nature versus nurture.

Yvan Arsenijevic

Open access · greenAbstract readReview
PubMed Publisher
In one paragraph

Review in Molecular neurobiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. p73 regulates maintenance of neural stem cell.Biochemical and biophysical research communications · 2010
    Article
  4. Article
  5. Bmi1 loss produces an increase in astroglial cells and a decrease in neural stem cell population and proliferation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2005
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Yvan ArsenijevicDepartment of Ophthalmology, Jules Gonin Eye Hospital, Lusanne University Medical School, Switzerland. Yvan.Arsenijevic@chuv.hospvd.ch
Hôpital Ophtalmique Jules-Gonin · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent data show that the final events of mammalian brain organogenesis may depend in part on the direct control of neural stem cell (NSC) proliferation and survival. Environmental and intrinsic factors play a role throughout development and during adulthood to regulate NSC proliferation. The NSCs acquire new competences throughout development, including adulthood, and this change in competence is region-specific. The factors controlling NSC survival, undifferentiated state, proliferation, and cell-cycle number are beginning to be identified, but the links between them remain unclear. However, current knowledge should help to formulate an understanding of how a stem cell can generate a new stem cell.

Indexed as

AnimalsBrainCell DifferentiationCell DivisionCell LineageGene Expression Regulation, DevelopmentalHumansNerve Growth FactorsNeurogliaNeuronsStem CellsNerve Growth Factors

Identifiers

PMID12668902
OpenAlexW2333640979

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.