ArticleThe Korean journal of parasitology2003
Excretory-secretory antigen is better than crude antigen for the serodiagnosis of clonorchiasis by ELISA.
Article in The Korean journal of parasitology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed.
- One-pot nanoflower-based sensitive colorimetric biosensor for multihost detection of zoonotic clonorchiasis.PLoS neglected tropical diseases · 2026Article
- The role of liver fluke invasion in the pathogenesis of cholangiocarcinoma.Clinical and experimental hepatology · 2026Review
- Clonorchiasis and opisthorchiasis: epidemiology, transmission, clinical features, morbidity, diagnosis, treatment, and control.Clinical microbiology reviews · 2024Review
- Silencing ofFrontiers in cellular and infection microbiology · 2022Article
- Clinical Characteristics ofFrontiers in medicine · 2021Article
- Serodiagnostic antigens of Clonorchis sinensis identified and evaluated by high-throughput proteogenomics.PLoS neglected tropical diseases · 2020Article
- Clonorchiasis in Patients with Biliary and Pancreatic Diseases: Diagnosis and Risk Factors.BioMed research international · 2020Article
- Cs1, a Clonorchis sinensis-derived serodiagnostic antigen containing tandem repeats and a signal peptide.PLoS neglected tropical diseases · 2018Article
- Significance of Serology by Multi-Antigen ELISA for Tissue Helminthiases in Korea.Journal of Korean medical science · 2017Article
- Enzyme-linked immunosorbent assay for diagnosis of Amphimerus spp. liver fluke infection in Humans.Memorias do Instituto Oswaldo Cruz · 2017Article
- Clonorchis sinensis, an oriental liver fluke, as a human biological agent of cholangiocarcinoma: a brief review.BMB reports · 2016Review
- Efficacy of Dot-ELISA using different antigens in detecting anti-schistosome antibodies among bovines in field conditions.Journal of parasitic diseases : official organ of the Indian Society for Parasitology · 2016Article
- Excretory/secretory products of the carcinogenic liver fluke are endocytosed by human cholangiocytes and drive cell proliferation and IL6 production.International journal for parasitology · 2015Article
- An outbreak of trichinellosis by consumption of raw soft-shelled turtle meat in Korea.The Korean journal of parasitology · 2015Article
- Infection status of endoparasites in foreigner workers living in Cheonan City, Chungnam Province, Korea.The Korean journal of parasitology · 2015Article
- Transcriptome sequencing and analysis of the zoonotic parasite Spirometra erinacei spargana (plerocercoids).Parasites & vectors · 2014Article
- The serological diagnosis of human clonorchiasis by time-resolved fluoroimmunoassay based on GST2-specific IgG4 detection.Parasitology research · 2014Article
- Pediatric neurocysticercosis: usefulness of antibody response in cysticidal treatment follow-up.BioMed research international · 2014Article
- Expression, immunolocalization, and serological reactivity of a novel sphingomyelin phosphodiesterase-like protein, an excretory/secretory antigen from Clonorchis sinensis.Parasitology research · 2013Article
- Trichinosis caused by ingestion of raw soft-shelled turtle meat in Korea.The Korean journal of parasitology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although stool examination is the standard diagnostic method of clonorchiasis, serodiagnosis by ELISA using crude antigen is now widely used because of its convenience. However, ELISA diagnosis still suffers from cross-reactions, and therefore there is a need to improve the present conventional ELISA. The present study was undertaken to evaluate the diagnostic value of ELISA using excretory-secretory antigen (ESA) instead of crude antigen (CA) of Clonorchis sinensis. The diagnostic sensitivity of ELISA using excretory-secretory antigen was 92.5%, which was higher than that of ELISA using crude Clonorchis sinensis antigen (88.2%). In addition, the specificity of excretory-secretory antigen was found 93.1% while that of crude antigen was 87.8%. In summary, Clonorchis sinensis ESA was found to be a better serodiagnostic antigen than CA for ELISA.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.