ArticleJournal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology2003
Cell responses to single pheromone molecules may reflect the activation kinetics of olfactory receptor molecules.
Article in Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Article
- Adaptive integrate-and-fire model reproduces the dynamics of olfactory receptor neuron responses in a moth.Journal of the Royal Society, Interface · 2019Article
- Kinetics of olfactory responses might largely depend on the odorant-receptor interaction and the odorant deactivation postulated for flux detectors.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2013Review
- Dynamical modeling of the moth pheromone-sensitive olfactory receptor neuron within its sensillar environment.PloS one · 2011Article
- Pheromone transduction in moths.Frontiers in cellular neuroscience · 2010Article
- Modelling and sensitivity analysis of the reactions involving receptor, G-protein and effector in vertebrate olfactory receptor neurons.Journal of computational neuroscience · 2009Article
- Olfactory perireceptor and receptor events in moths: a kinetic model revised.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2009Review
- Computational model of the insect pheromone transduction cascade.PLoS computational biology · 2009Article
- Representation of a mixture of pheromone and host plant odor by antennal lobe projection neurons of the silkmoth Bombyx mori.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2008Article
- Dynamic properties of Drosophila olfactory electroantennograms.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2008Article
- Efficient olfactory coding in the pheromone receptor neuron of a moth.PLoS computational biology · 2008Article
- Chemosensory coding by neurons in the coeloconic sensilla of the Drosophila antenna.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2005Article
Corrections and comments
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Authors and funding
2 authors.
Funding
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Abstract
Olfactory receptor cells of the silkmoth Bombyx mori respond to single pheromone molecules with "elementary" electrical events that appear as discrete "bumps" a few milliseconds in duration, or bursts of bumps. As revealed by simulation, one bump may result from a series of random openings of one or several ion channels, producing an average inward membrane current of 1.5 pA. The distributions of durations of bumps and of gaps between bumps in a burst can be fitted by single exponentials with time constants of 10.2 ms and 40.5 ms, respectively. The distribution of burst durations is a sum of two exponentials; the number of bumps per burst obeyed a geometric distribution (mean 3.2 bumps per burst). Accordingly the elementary events could reflect transitions among three states of the pheromone receptor molecule: the vacant receptor (state 1), the pheromone-receptor complex (state 2), and the activated complex (state 3). The calculated rate constants of the transitions between states are k(21)=7.7 s(-1), k(23)=16.8 s(-1), and k(32)=98 s(-1).
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