ArticleParasitology research2003
Molecular diagnosis of Chagas' disease and use of an animal model to study parasite tropism.
Article in Parasitology research, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 47 citations in OpenAlex.
- The End Justifies the Means: Chagas Disease from a Perspective of the Host-Life (Basel, Switzerland) · 2024Review
- Article
- Cardiomyocyte oxidants production may signal to T. cruzi intracellular development.PLoS neglected tropical diseases · 2017Article
- Are Members of the Triatoma brasiliensis (Hemiptera, Reduviidae) Species Complex Able to Alter the Biology and Virulence of a Trypanosoma cruzi Strain?Neotropical entomology · 2015Article
- Projected future distributions of vectors of Trypanosoma cruzi in North America under climate change scenarios.PLoS neglected tropical diseases · 2014Article
- Exacerbated skeletal muscle inflammation and calcification in the acute phase of infection by Mexican Trypanosoma cruzi DTUI strain.BioMed research international · 2014Article
- Biologic and genetics aspects of chagas disease at endemic areas.Journal of tropical medicine · 2012Article
- Gastrointestinal infection with Mexican TcI Trypanosoma cruzi strains: different degrees of colonization and diverse immune responses.International journal of biological sciences · 2011Article
- Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling.BMC genomics · 2009Article
- Influence of Trypanosoma cruzi chronic infection in the depletion of esophageal neurons in Calomys callosus.Digestive diseases and sciences · 2006Article
- Pathology affects different organs in two mouse strains chronically infected by a Trypanosoma cruzi clone: a model for genetic studies of Chagas' disease.Infection and immunity · 2004Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chagas' disease, which is an important health problem in humans, is caused by the protozoan Trypanosoma cruzi. The cellular and molecular mechanisms, involved in the selective tropism of T. cruzi to different organs remain largely unknown. In this study we designed a PCR-based molecular diagnosis method in order to study the tropism and growth kinetics of T. cruzi in a murine model infected with parasites isolated from an endemic area of Mexico. The growth kinetics and parasite tropism of T. cruzi were also evaluated in the blood and other tissues. We observed that T. cruzi isolates from the Western Mexico showed a major tropism to mouse heart and skeletal muscles in this murine model.
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