Evidence map›Paper›PMID 12656640›Full record

ReviewSports medicine (Auckland, N.Z.)2003

Drugs for increasing oxygen and their potential use in doping: a review.

Aurelie Gaudard, Emmanuelle Varlet-Marie, Francoise Bressolle, Michel Audran

Abstract readReview
PubMed Publisher
In one paragraph

Review in Sports medicine (Auckland, N.Z.), 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Article
  3. Hepcidin and sports anemia.Cell & bioscience · 2014
    Review
  4. Review
  5. Erythropoietin use and abuse.Indian journal of endocrinology and metabolism · 2012
    Article
  6. Variability in training-induced skeletal muscle adaptation.Journal of applied physiology (Bethesda, Md. : 1985) · 2011
    Review
  7. Article
  8. Review
  9. Oxygen delivery enhancers: past, present, and future.Journal of endocrinological investigation · 2008
    Review
  10. Article
  11. Review
  12. Review
  13. Gene doping in sports.Sports medicine (Auckland, N.Z.) · 2004
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Aurelie GaudardClinical Pharmacokinetic Laboratory, Faculty of Pharmacy, University Montpellier I, Montpellier, France.
Emmanuelle Varlet-Marie
Francoise Bressolle
Michel Audran
Université de Montpellier · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blood oxygenation is a fundamental factor in optimising muscular activity. Enhancement of oxygen delivery to tissues is associated with a substantial improvement in athletic performance, particularly in endurance sports. Progress in medical research has led to the identification of new chemicals for the treatment of severe anaemia. Effective and promising molecules have been created and sometimes used for doping purposes. The aim of this review is to present methods, and drugs, known to be (or that might be) used by athletes to increase oxygen transport in an attempt to improve endurance capacity. These methods and drugs include: (i) blood transfusion; (ii) endogenous stimulation of red blood cell production at altitude, or using hypoxic rooms, erythropoietins (EPOs), EPO gene therapy or EPO mimetics; (iii) allosteric effectors of haemoglobin; and (iv) blood substitutes such as modified haemoglobin solutions and perfluorochemicals. Often, new chemicals are used before safety tests have been completed and athletes are taking great health risks. Such new chemicals have also created the need for new instrumental strategies in doping control laboratories, but not all of these chemicals are detectable. Further progress in analytical research is necessary.

Indexed as

AltitudeBlood SubstitutesDarbepoetin alfaDoping in SportsEpoetin AlfaErythropoietinExerciseGenetic TherapyHemoglobinsHumansMolecular MimicryOxygenOxygen ConsumptionPhysical EnduranceRecombinant ProteinsSubstance Abuse DetectionBlood SubstitutesDarbepoetin alfaEpoetin AlfaErythropoietinHemoglobinsOxygenRecombinant Proteins

Identifiers

PMID12656640
OpenAlexW1473544247

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.