ArticleInfection and immunity2003
Passive immunity in Helicobacter-challenged neonatal mice conferred by immunized dams lasts until weaning.
Article in Infection and immunity, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 14 citations in OpenAlex.
- Immune responses to Helicobacter pylori infection.World journal of gastroenterology · 2014Review
- Mucosal IgA & IL-1β in Helicobacter pylori Infection.Indian journal of clinical biochemistry : IJCB · 2013Article
- Antibody-mediated protection against infection with Helicobacter pylori in a suckling mouse model of passive immunity.Infection and immunity · 2009Article
- Influence of age and duration of infection on bacterial load and immune responses to Helicobacter pylori infection in a murine model.Clinical and experimental immunology · 2005Article
- The Helicobacter felis model of adoptive transfer gastritis.Immunologic research · 2005Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective of this study was to examine the effect of breast-feeding by immunized dams on Helicobacter colonization in newborns. Urease-based immunization regimens failed to protect nursing pups against H. felis, whereas H. felis lysate-cholera toxin resulted in protection. This observation correlated with a high recognition of cell surface-expressed bacterial antigens by milk antibodies. Protection lasted until weaning, indicating that infection is maintained at undetectable levels by passive immunity but then resumes when breast-feeding stops.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.