ArticlePlant physiology2003
A novel Cl- inward-rectifying current in the plasma membrane of the calcifying marine phytoplankton Coccolithus pelagicus.
Article in Plant physiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 49 citations in OpenAlex.
- Reduced HProceedings of the National Academy of Sciences of the United States of America · 2022Article
- Origins of eukaryotic excitability.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- A Novel Single-Domain NaPlant physiology · 2020Article
- Novel Electrical Signaling: First Fast Voltage-Gated Sodium Channel Identified Outside of the Animal Kingdom.Plant physiology · 2020Article
- Alternative Mechanisms for Fast NaCurrent biology : CB · 2019Article
- Dynamic changes in carbonate chemistry in the microenvironment around single marine phytoplankton cells.Nature communications · 2018Article
- Interaction of a dinoflagellate neurotoxin with voltage-activated ion channels in a marine diatom.PeerJ · 2018Article
- Biotic Control of Surface pH and Evidence of Light-Induced H+ Pumping and Ca2+-H+ Exchange in a Tropical Crustose Coralline Alga.PloS one · 2016Article
- Voltage-gated proton channels: molecular biology, physiology, and pathophysiology of the H(V) family.Physiological reviews · 2013Review
- Osmotic stress triggers toxin production by the dinoflagellate Karenia brevis.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- A voltage-gated H+ channel underlying pH homeostasis in calcifying coccolithophores.PLoS biology · 2011Article
- A fast Na+/Ca2+-based action potential in a marine diatom.PloS one · 2009Article
- Elucidation of the mechanisms underlying hypo-osmotically induced turgor pressure regulation in the marine alga Valonia utricularis.The Journal of membrane biology · 2006Article
- Protoplast formation of the coccolithophorid Pleurochrysis haptonemofera in hypoosmotic K+ solution: shedding of the coccosphere and regrowth of the protoplast in normal medium.Marine biotechnology (New York, N.Y.)Article
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the membrane properties and dominant ionic conductances in the plasma membrane of the calcifying marine phytoplankton Coccolithus pelagicus using the patch-clamp technique. Whole-cell recordings obtained from decalcified cells revealed a dominant anion conductance in response to membrane hyperpolarization. Ion substitution showed that the anion channels were selective for Cl(-) and Br(-) over other anions, and the sensitivity to the stilbene derivative 4,4'-diisothiocyanatostilbene-2,2'-disulfonic acid, ethacrynic acid, and Zn(2+) revealed a pharmacological profile typical of many plant and animal anion channels. Voltage activation and kinetic characteristics of the C. pelagicus Cl(-) channel are consistent with a novel function in plants as the inward rectifier that tightly regulates membrane potential. Membrane depolarization gave rise to nonselective cation currents and in some cases evoked action potential currents. We propose that these major ion conductances play an essential role in membrane voltage regulation that relates to the unique transport physiology of these calcifying phytoplankton.
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