Evidence map›Paper›PMID 12644513›Full record

ArticleJournal of bacteriology2003

Analysis of the ferric citrate transport gene promoter of Escherichia coli.

Sabine Enz, Susanne Mahren, Claudia Menzel, Volkmar Braun

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sabine EnzMikrobiologie/Membranphysiologie, Universität Tübingen, Germany.
Susanne Mahren
Claudia Menzel
Volkmar Braun
University of Tübingen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

FecI, an extracytoplasmic-function sigma factor, is required for initiation of transcription of the ferric citrate transport genes. A mutational analysis of the fecA promoter revealed that the nonconserved -10 region and a downstream regulatory element are important for fecA promoter activity. However, nucleotide substitutions in the well-conserved -35 region also have an effect on the fecA promoter activity. Titration of FecI suggests that the FecI-RNA polymerase holoenzyme does not bind strongly to the downstream regulatory element, which is therefore probably involved in a subsequent step of transcription initiation.

Indexed as

Promoter Regions, GeneticReceptors, Cell SurfaceBase SequenceBiological TransportCarrier ProteinsEscherichia coliEscherichia coli ProteinsFerric CompoundsGreen Fluorescent ProteinsLuminescent ProteinsMolecular Sequence DataPoint MutationRecombinant ProteinsTranscription Initiation SiteCarrier ProteinsEscherichia coli ProteinsFecA protein, E coliferric citrateFerric CompoundsGreen Fluorescent ProteinsLuminescent ProteinsReceptors, Cell SurfaceRecombinant Proteins

Identifiers

PMID12644513
PMCPMC151517
OpenAlexW2096101482

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.