Evidence map›Paper›PMID 12639985›Full record

ArticleThe Journal of clinical investigation2003

The challenge of molecular medicine: complexity versus Occam's razor.

Eric A Sobie, Silvia Guatimosim, Long-Sheng Song, W J Lederer

Abstract readCommentComparative Study
In one paragraph

Article in The Journal of clinical investigation, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Remodeling of calcium handling in human heart failure.Advances in experimental medicine and biology · 2012
    Review
  2. Article
  3. Orphaned ryanodine receptors in the failing heart.Proceedings of the National Academy of Sciences of the United States of America · 2006
    Article
  4. Return of calcium: manipulating intracellular calcium to prevent cardiac pathologies.Proceedings of the National Academy of Sciences of the United States of America · 2004
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Eric A SobieMedical Biotechnology Center, University of Maryland Biotechnology Institute, Baltimore, Maryland 21201, USA.
Silvia Guatimosim
Long-Sheng Song
W J Lederer

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Disease Models, AnimalAnimalsCalcium-Binding ProteinsCardiomegalyCardiomyopathy, DilatedHeart FailureHumansMicePhospholambanCalcium-Binding ProteinsPhospholamban

Identifiers

PMID12639985
PMCPMC153775

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.