ReviewEnvironmental health perspectives2002
Application of genomics to toxicology research.
Review in Environmental health perspectives, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Computational Strategies for Assessing Adverse Outcome Pathways: Hepatic Steatosis as a Case Study.International journal of molecular sciences · 2024Review
- New "Omics" Approaches as Tools to Explore Mechanistic Nanotoxicology.Advances in experimental medicine and biology · 2022Article
- A decade of toxicological trends: what the papers say.Toxicology research · 2020Review
- The aryl hydrocarbon receptor: a perspective on potential roles in the immune system.Immunology · 2009Review
- Assessing cumulative health risks from exposure to environmental mixtures - three fundamental questions.Environmental health perspectives · 2007Article
- Chemical mixtures: considering the evolution of toxicology and chemical assessment.Environmental health perspectives · 2005Article
- Toxicogenomics of subchronic hexachlorobenzene exposure in Brown Norway rats.Environmental health perspectives · 2004Article
- Database development in toxicogenomics: issues and efforts.Environmental health perspectives · 2004Review
- Aryl Hydrocarbon Receptor (AhR) Ligands as Selective AhR Modulators: Genomic Studies.Current opinion in toxicologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
Traditional models of toxicity have relied on dissecting chemical action into pharmacokinetic and pharmacodynamic processes. However, the integration of genomic information with toxicology will enhance our basic understanding of these processes and significantly change the way we apply toxicological information to risk assessment and regulatory problems. In this article, we summarize the application of gene expression information and polymorphism discovery to four areas in toxicology: toxicity testing, cross-species extrapolation, understanding mechanism of action, and susceptibility.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.