Evidence map›Paper›PMID 12631457›Full record

ReviewCurrent gastroenterology reports2003

Effects of bioactive agents on biliary motor function.

Charmaine M Woods, Gary M Mawe, Eldon A Shaffer, James Toouli, Gino T P Saccone

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current gastroenterology reports, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Electrical activation of common bile duct nerves modulates sphincter of Oddi motility in the Australian possum.HPB : the official journal of the International Hepato Pancreato Biliary Association · 2005
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Charmaine M WoodsDepartment of General and Digestive Surgery, Flinders University of South Australia, Adelaide, Australia 5042. gino.saccone@flinders.edu.au
Gary M Mawe
Eldon A Shaffer
James Toouli
Gino T P Saccone
Flinders University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our understanding of biliary motility under normal and pathophysiologic conditions is still incomplete, but there have been recent advances. Of particular interest are the mechanisms involved in gallbladder filling and emptying, with a focus on understanding the processes underlying impaired gallbladder emptying leading to gallbladder dyskinesia and the formation of gallstones or cholecystitis. The sphincter of Oddi (SO) is a complex neuromuscular structure. Recent studies have attempted to unravel the specific neural or hormonal mechanisms operating under normal physiologic conditions and those that may lead to SO dysfunction. Furthermore, new research fronts are emerging, including the role of leptin in obese patients with impaired biliary motility and the action of electroacupuncture for possible treatment of SO dysfunction. This review illustrates the broad front of current research regarding the effects of bioactive agents on biliary motility, including enteric hormones, nitric oxide, opioids, inflammatory mediators, leptin, protease inhibitors, neurotransmitters, and electroacupuncture.

Indexed as

AnimalsBiliary TractElectroacupunctureGabexateGallbladderGallbladder EmptyingHistamineHumansImmunohistochemistryInflammation MediatorsLeptinNeurotransmitter AgentsPancreatitisSerine Proteinase InhibitorsSincalideSomatostatinGabexateHistamineInflammation MediatorsLeptinNeurotransmitter AgentsSerine Proteinase InhibitorsSincalideSomatostatin

Identifiers

PMID12631457
OpenAlexW2055157205

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.