Evidence map›Paper›PMID 12630331›Full record

ArticleFolia microbiologica2002

Production of interferons and change of the lymphocyte subpopulation phenotype in peripheral blood at cervical papillomavirus infection.

L Lazarenko, M Spivak, V Lakatosh, L Kryvokhatska, O Mikhailenko, A Rudenko, L Tkáciková, I Mikula

Abstract read
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In one paragraph

Article in Folia microbiologica, 2002. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

L LazarenkoZabolotny Institute of Microbiology and Virology, National Academy of Sciences of Ukraine, Kiev, Ukraine.
M Spivak
V Lakatosh
L Kryvokhatska
O Mikhailenko
A Rudenko
L Tkáciková
I Mikula
Danylo Zabolotny Institute of Microbiology and Virology · UABogomolets National Medical University · UAUniversity of Veterinary Medicine in Košice · SKInstitute of Urology of the National Academy of Medical Sciences of Ukraine · UA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

IFN-gamma and IFN-alpha production in vitro by peripheral blood cells activated by phytohemagglutinin or the Newcastle disease virus was impaired in patients with a benign process, cervical intraepithelial neoplasm and cancer in situ associated with human papillomavirus infection. In case of IFN-gamma and IFN-alpha production impairment following cervical papillomavirus infection, the increased severity of disease was accompanied by remarkable IFN system suppression. The lower synthesis of both IFN correlated with changes of some lymphocyte-subpopulation phenotype in peripheral blood. Lower CD4+ and CD3+ DR+ T cell concentrations were observed in papillomavirus-infected patients with impaired IFN production; impaired IFN-gamma production was accompanied by lower CD4/CD8 index.

Indexed as

PapillomaviridaeAdultCarcinoma in SituFemaleHumansInterferon-alphaInterferon-gammaLymphocyte SubsetsNewcastle disease virusPapillomavirus InfectionsPhytohemagglutininsUterine Cervical DysplasiaUterine Cervical NeoplasmsInterferon-alphaInterferon-gammaphytohemagglutinin-PPhytohemagglutinins

Identifiers

PMID12630331
OpenAlexW2012347271

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.