ArticleDiabetologia2003
High prevalence of undiagnosed diabetes mellitus in Southern Germany: target populations for efficient screening. The KORA survey 2000.
Article in Diabetologia, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 174 papers, 5 of them syntheses that pooled it.
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Who cites it
174 citing papers in PubMed, 5 syntheses or guidelines pooled it, 550 citations in OpenAlex.
- The worldwide trend in diabetes awareness, treatment, and control from 1985 to 2022: a systematic review and meta-analysis of 233 population-representative studies.Frontiers in public health · 2024Pooled it
- The Burden of Undiagnosed Diabetes Mellitus in Adult African Population: A Systematic Review and Meta-Analysis.Journal of diabetes research · 2019Pooled it
- Development of type 2 diabetes mellitus in people with intermediate hyperglycaemia.The Cochrane database of systematic reviews · 2018Pooled it
- Pooled it
- Gender differences in the metabolic syndrome and their role for cardiovascular disease.Clinical research in cardiology : official journal of the German Cardiac Society · 2006Pooled it
- The prevalence and correlates of pre-diabetes in middle- to older-aged Irish adults using three diagnostic methods.PloS one · 2021Trial
- Trial
- PLA1A2 platelet polymorphism predicts mortality in prediabetic subjects of the population based KORA S4-Cohort.Cardiovascular diabetology · 2014Trial
- Cognitive behavioural therapy in elderly type 2 diabetes patients with minor depression or mild major depression: study protocol of a randomized controlled trial (MIND-DIA).BMC geriatrics · 2010Trial
- Blood glucose testing and primary prevention of diabetes mellitus type 2--evaluation of the effect of evidence based patient information.BMC public health · 2010Trial
- A narrative review of what cohorts have taught us and how they have laid the foundation for much of our understanding of type 2 diabetes.Diabetologia · 2026Review
- Differential associations of dietary patterns with estimated 10-year cardiovascular risk in diabetes subtypes.Scientific reports · 2026Observational
- Association of the phase angle with type 2 diabetes and related traits: results from two prospective KORA studies.Nutrition & diabetes · 2026Article
- Workplace-Based Glucose Screening for Type 2 Diabetes in French Civil Servants: Prospective Observational Cohort Study.JMIR public health and surveillance · 2025Observational
- Cohort Profile: Cooperative Health Research in the Region of Augsburg (KORA) 1984-2024.International journal of epidemiology · 2025Article
- Lung function in elderly subjects with metabolic syndrome and type II diabetes : Data from the Berlin Aging Study II.Zeitschrift fur Gerontologie und Geriatrie · 2025Article
- Associations of carbohydrate quality and cardiovascular risk factors vary among diabetes subtypes.Cardiovascular diabetology · 2025Observational
- Association of plasma proteomics with mortality in individuals with and without type 2 diabetes: Results from two population-based KORA cohort studies.BMC medicine · 2024Article
- Plasma infrared fingerprinting with machine learning enables single-measurement multi-phenotype health screening.Cell reports. Medicine · 2024Article
- Omentin associates with serum metabolite profiles indicating lower diabetes risk: KORA F4 Study.BMJ open diabetes research & care · 2024Article
114 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aims/hypothesisTo estimate the prevalence of undiagnosed diabetes mellitus, impaired glucose tolerance (IGT) and impaired fasting glucose (IFG), and their relations with cardiovascular risk factors in the general population aged 55 to 74 years in Southern Germany.
methodsOral glucose tolerance tests were carried out in a random sample of 1353 subjects aged 55 to 74 years participating in the KORA (Cooperative Health Research in the Region of Augsburg) Survey 2000. Prevalences of glucose tolerance categories (1999 WHO criteria) were adjusted for sample probabilities. The numbers needed to screen (NNTS) to identify one person with undiagnosed diabetes were estimated from age-adjusted logistic regression models.
resultsSample design-based prevalences of known and unknown diabetes, IGT, and IFG were 9.0%, 9.7%, 16.8%, 9.8% in men, and 7.9%, 6.9%, 16.0%, 4.5% in women, respectively. In both sexes, participants with undiagnosed diabetes had higher BMI, waist circumference, systolic blood pressure, triglycerides, uric acid, and lower HDL-cholesterol than normoglycaemic subjects. A combination of abdominal adiposity, hypertension, and parental diabetes in men resulted in a NNTS of 2.9 (95%CI: 2.0-4.6). In women, the combination of increased triglycerides, hypertension and parental diabetes history yielded a NNTS of 3.2 (95%CI: 2.2-5.1). CONCLUSION/
interpretationAbout 40% of the population aged 55 to 74 years in the Augsburg region have disturbed glucose tolerance or diabetes. Half of the total cases with diabetes are undiagnosed. Cardiovascular risk factors worsen among glucose tolerance categories, indicating the need for screening and prevention. Screening for undiagnosed diabetes could be most efficient in individuals with abdominal adiposity (men), hypertriglyceridaemia (women), hypertension, and parental diabetes history.
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