Evidence map›Paper›PMID 12627300›Full record

Trial reportEuropean journal of applied physiology2003

Changes in blood lipid peroxidation markers and antioxidants after a single sprint anaerobic exercise.

C Groussard, F Rannou-Bekono, G Machefer, M Chevanne, S Vincent, O Sergent, J Cillard, A Gratas-Delamarche

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 1 synthesis or guideline pooled it.

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3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

C GroussardLaboratoire de Physiologie et de Biomécanique de l'Exercice Musculaire, Campus la Harpe, UFRAPS Rennes 2, EA 1274, Avenue Charles Tillon, CS 24414, 35044 Rennes Cedex, France. carole.groussard@uhb.fr
F Rannou-Bekono
G Machefer
M Chevanne
S Vincent
O Sergent
J Cillard
A Gratas-Delamarche

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It has been well demonstrated that the principal factor responsible for oxidative damage during exercise is the increase in oxygen consumption. However, other theoretical factors (acidosis, catecholamine autoxidation, ischemia-reperfusion syndrome, etc.) that are known to induce, in vitro, oxidative damage may also be operative during short-term supramaximal anaerobic exercise. Therefore, we hypothesized that short-term supramaximal anaerobic exercise (30-s Wingate test) could induce an oxidative stress. Lipid peroxidation markers [serum lipid radical production detected by electron spin resonance (ESR) spectroscopy and plasma malondialdehyde (MDA) levels detected by the thiobarbituric acid reactive substances (TBARS) method], as well as erythrocyte antioxidant enzyme activities [glutathione peroxidase (GPx), superoxide dismutase (SOD)] and erythrocyte glutathione (GSH) levels, were measured at rest, after the Wingate test and during the 40 min of recovery. The recovery of exercise was associated with a significant increase (x2.7) in lipid radical production detected by ESR spectroscopy, as well as with changes in the erythrocyte GSH level (-13.6%) and SOD activity (-11.7%). The paradoxical decrease in plasma TBARS (-23.7%) which was correlated with the peak power developed during the Wingate test ( r=-0.7), strongly suggests that such exercise stimulates the elimination of MDA. In conclusion, this study demonstrates that short-term supramaximal anaerobic exercise induces an oxidative stress and that the plasma TBARS level is not a suitable marker during this type of exercise.

Indexed as

AdultAnaerobiosisAntioxidantsBiomarkersEnzyme ActivationErythrocytesExercise TestExercise ToleranceGlutathioneGlutathione PeroxidaseHumansLipid PeroxidationLipidsMaleMalondialdehydeOxidative StressAntioxidantsBiomarkersGlutathioneGlutathione PeroxidaseLipidsMalondialdehydeSuperoxide Dismutase

Identifiers

PMID12627300

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.