Evidence map›Paper›PMID 12626463›Full record

ArticleClinical and diagnostic laboratory immunology2003

Nucleoporin p62 antibodies in a case of mixed connective tissue disease.

Doris M Kraemer, Michael R Kraus, Christian Kneitz, Hans-Peter Tony

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Clinical and diagnostic laboratory immunology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Autoantigens of the nuclear pore complex.Journal of molecular medicine (Berlin, Germany) · 2004
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Doris M KraemerMedizinische Poliklinik, University of Wurzburg, 97070 Wurzburg, Germany. d.kraemer@medizin.uni-wuerzburg.de
Michael R Kraus
Christian Kneitz
Hans-Peter Tony
University of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mixed connective tissue disease is an overlap syndrome characterized by features of different systemic autoimmune diseases and a high titer of U1-snRNP antibodies. We examine here the autoantibodies to nucleoporin p62 in a severe case of mixed connective tissue disease in a young male patient. Thus far, p62 antibodies have mainly been described in cases of primary biliary cirrhosis. We speculate that the presence of p62 antibodies is an indication of a poor prognosis in connective tissue disorders.

Indexed as

AdultAutoantibodiesHeLa CellsHumansMaleMembrane GlycoproteinsMixed Connective Tissue DiseaseNuclear Pore Complex ProteinsPrognosisAutoantibodiesMembrane GlycoproteinsNuclear Pore Complex Proteinsnuclear pore protein p62

Identifiers

PMID12626463
PMCPMC150528
OpenAlexW2145242726

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.