Evidence map›Paper›PMID 12624611›Full record

Trial reportJournal of human hypertension2003

Effectiveness of multidisciplinary lifestyle intervention for hypertension: a randomised controlled trial.

R Mattila, A Malmivaara, M Kastarinen, S-L Kivelä, A Nissinen

Registry-linked trialAbstract readClinical TrialRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Journal of human hypertension, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01741428 ("Hjerteloeftet". Early Interventions to Promote Physical Activity, Dietary Lifestyle Changes and Optimal Medication for Cardiovascular Risk Factor Reduction in Over 3 Years Follow-up.), which is not on this map. Cited by 29 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 12 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01741428 nacompletednot on this mapstarted 2012, after this paper: background citation

"Hjerteloeftet". Early Interventions to Promote Physical Activity, Dietary Lifestyle Changes and Optimal Medication for Cardiovascular Risk Factor Reduction in Over 3 Years Follow-up.

TypeinterventionalSponsorLHL HelseRan2012 to 2019Enrolled701ConditionsCardiovascular DiseaseArmsIntervention (INT1)
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 12 syntheses or guidelines pooled it.

  1. Pooled it
  2. Impact of patient care teams on blood pressure control in patients with hypertension: a systematic review and meta-analysis.Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Pooled it
  3. Group-delivered interventions for lowering blood pressure in hypertension: a systematic review and meta-analysis.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025
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  8. Effect of longer-term modest salt reduction on blood pressure.The Cochrane database of systematic reviews · 2013
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  12. Interventions for promoting physical activity.The Cochrane database of systematic reviews · 2005
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

R MattilaRehabilitation Centre Korpilampi, Espoo, Finland. riikka.mattila@korpilampi.com
A Malmivaara
M Kastarinen
S-L Kivelä
A Nissinen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lifestyle factors like weight, alcohol consumption, salt intake and physical activity have shown to be important in treating hypertension. There have been made some randomised trials about the effects of lifestyle interventions, but the numbers of patients have been relatively small and the durations of follow-ups have been short. No controlled trials assessing the effects of lifestyle intervention in a rehabilitation setting have been reported. In this study, the effects of multidisciplinary lifestyle intervention in rehabilitation centres among middle-aged hypertensive employees were described. A total of 731 hypertensives from 45 worksites were randomised to lifestyle intervention in a rehabilitation centre or to usual care in an occupational or primary health-care centre for 12 months. Standard measurements were conducted before the intervention and 1-year later. Blood pressure (BP) levels were clearly reduced in the intervention group, while only minor changes were observed in the control group. The net changes between the two groups both for systolic and diastolic BPs were -2.1 mmHg (95% confidence intervals (CI) -4.0 to -0.1) and -1.5 mmHg (95% CI -2.6 to -0.4), respectively. The net changes were greater among men than women. The multidisciplinary lifestyle intervention in a rehabilitation centre setting produced significant reductions in BP among middle-aged employees with hypertension.

Indexed as

Health BehaviorPatient Care TeamCardiovascular DiseasesCounselingFemaleFollow-Up StudiesHumansHypertensionLife StyleMaleMiddle AgedPatient Education as TopicRisk Factors

Identifiers

PMID12624611

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.