Trial reportVeterinary parasitology2003
Prevalence and control of bovine cryptosporidiosis in German dairy herds.
Trial report in Veterinary parasitology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.
- Efficacy of halofuginone products to prevent or treat cryptosporidiosis in bovine calves: a systematic review and meta-analyses.Parasitology · 2021Pooled it
- Utility of halofuginone lactate for the prevention of natural cryptosporidiosis of calves, in the presence of co-infection with rotavirus and Salmonella Typhimurium.Veterinary parasitology · 2013Trial
- Integration of halofuginone lactate treatment and disinfection with p-chloro-m-cresol to control natural cryptosporidiosis in calves.Veterinary parasitology · 2013Trial
- Control of cryptosporidiosis in neonatal calves: use of halofuginone lactate in two different calf rearing systems.Preventive veterinary medicine · 2010Trial
- Article
- Past, current, and potential treatments for cryptosporidiosis in humans and farm animals: A comprehensive review.Frontiers in cellular and infection microbiology · 2023Review
- Distribution of Cryptosporidium parvum gp60 subtypes in calf herds of Saxony, Germany.Parasitology research · 2019Article
- Long-term use of yeast fermentation products in comparison to halofuginone for the control of cryptosporidiosis in neonatal calves.Veterinary parasitology · 2019Article
- Cryptosporidium outbreak in calves on a large dairy farm: Effect of treatment and the association with the inflammatory response and short-term weight gain.Research in veterinary science · 2018Article
- Bovine cryptosporidiosis: impact, host-parasite interaction and control strategies.Veterinary research · 2017Review
- Cryptosporidium parvum infection and associated risk factors in dairy calves in western France.Preventive veterinary medicine · 2015Article
- Molecular and parasitological study of cryptosporidium isolates from cattle in ilam, west of iran.Iranian journal of parasitology · 2014Article
- Giardiosis and other enteropathogenic infections: a study on diarrhoeic calves in Southern Germany.BMC research notes · 2014Article
- Molecular identification of Giardia and Cryptosporidium from dogs and cats.Parasite (Paris, France) · 2013Article
- Cryptosporidium infection in herds with and without calf diarrhoeal problems.Parasitology research · 2010Article
- Prophylactic and therapeutic efficacy of nitazoxanide against Cryptosporidium parvum in experimentally challenged neonatal calves.Veterinary parasitology · 2009Article
- The first detection of Cryptosporidium deer-like genotype in cattle in Japan.Parasitology research · 2009Article
- Preventive and therapeutic efficacy of halofuginone-lactate against Cryptosporidium parvum in spontaneously infected calves: a centralised, randomised, double-blind, placebo-controlled study.Veterinary journal (London, England : 1997) · 2008Article
- The public health and clinical significance of Giardia and Cryptosporidium in domestic animals.Veterinary journal (London, England : 1997) · 2008Review
- An Irish perspective on Cryptosporidium. Part 2.Irish veterinary journal · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In a 5-year survey regarding its prevalence and importance in five German state veterinary laboratories Cryptosporidium was diagnosed annually in 19-36% of faecal samples either submitted to the laboratories or taken post mortem. In approximately half of the cases no other enteropathogens were detected. However, only 73% of 30 laboratories participating in a questionnaire survey routinely tested for this parasite, and the majority of researchers considered cryptosporidiosis to be of minor importance. In a placebo-controlled field study 152 suckling calves were treated daily against cryptosporidiosis either with sulfadimidine or with halofuginone (Halocur, Intervet) over 1 week. Treatment by oral drench started at the onset of diarrhoea in the herd. Oocyst excretion, faecal consistency and health status were recorded five times for a 3-week period. Oocyst excretion peaked 7-14 days in the placebo group after the onset of diarrhoea, and during that period prevalence and intensity of excretion were significantly lower in the halofuginone-treated group compared to the sulfadimidine and the placebo control groups. The health status (diarrhoea, dehydration) declined in all groups but was significantly (P<0.05-0.001) better in the halofuginone group in the first 2 weeks. Halofuginone effectively (P<0.05-0.001) reduced oocyst excretion and improved the health status of the treated animals, while sulfadimidine had no effect against Cryptosporidium.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.