ArticleJournal of bacteriology2003
Gene expression profile of Campylobacter jejuni in response to growth temperature variation.
Article in Journal of bacteriology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 104 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
104 citing papers in PubMed.
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- Prevalence and antimicrobial resistance ofOne health (Amsterdam, Netherlands) · 2025Review
- Prevalence and genetic characteristics of Campylobacter jejuni from laying-hens in Hubei Province, China.BMC veterinary research · 2025Article
- High prevalence of antibiotic resistant Campylobacter among patients attending clinical settings in Kigali, Rwanda.BMC infectious diseases · 2025Article
- The Efficacy of a Ferric Sillen Core-Linked Polymer in Suppressing the Pathogenicity ofAnimals : an open access journal from MDPI · 2024Article
- Interplay of two small RNAs fine-tunes hierarchical flagella gene expression in Campylobacter jejuni.Nature communications · 2024Article
- Proteome profiling of Campylobacter jejuni 81-176 at 37 °C and 42 °C by label-free mass spectrometry.BMC microbiology · 2024Article
- Unravelling the transcriptome response of Enterobacter sp. S-33 under varying temperature.Archives of microbiology · 2024Article
- Zoonotic Bacteria inAnimals : an open access journal from MDPI · 2023Article
- Survival ofMicroorganisms · 2022Article
- Quantitative Assessment of First Nations Drinking Water Distribution Systems for Detection and Prevalence of ThermophilicInternational journal of environmental research and public health · 2022Article
- Genomic Analysis Reveals That Isolation Temperature on Selective Media Introduces Genetic Variation inPathogens (Basel, Switzerland) · 2022Article
- Feeling the Heat: TheBiomolecules · 2021Article
- Proteomic insights into Lysinibacillus sp.-mediated biosolubilization of manganese.Environmental science and pollution research international · 2021Article
- Staphylococcus aureus enhances biofilm formation, aerotolerance, and survival of Campylobacter strains isolated from retail meats.Scientific reports · 2021Article
- Functional analysis and cryo-electron microscopy ofGut microbes · 2020Article
- Zoonotic and Public Health Implications ofPathogens (Basel, Switzerland) · 2020Review
- The gastrointestinal pathogen Campylobacter jejuni metabolizes sugars with potential help from commensal Bacteroides vulgatus.Communications biology · 2020Article
44 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
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1 author.
Funding
Abstract
The foodborne pathogen Campylobacter jejuni is the primary causative agent of gastroenteritis in humans. In the present study a whole genome microarray of C. jejuni was constructed and validated. These DNA microarrays were used to measure changes in transcription levels over time, as C. jejuni cells responded to a temperature increase from 37 to 42 degrees C. Approximately 20% of the C. jejuni genes were significantly up- or downregulated over a 50-min period after the temperature increase. The global change in C. jejuni transcriptome was found to be essentially transient, with only a small subset of genes still differentially expressed after 50 min. A substantial number of genes with a downregulated coexpression pattern were found to encode for ribosomal proteins. This suggests a short growth arrest upon temperature stress, allowing the bacteria to reshuffle their energy toward survival and adaptation to the new growth temperature. Genes encoding chaperones, chaperonins, and heat shock proteins displayed the most dramatic and rapid upregulation immediately after the temperature change. Interestingly, genes encoding proteins involved in membrane structure modification were differentially expressed, either up- or downregulated, suggesting a different protein membrane makeup at the two different growth temperatures. Overall, these data provide new insights into the primary response of C. jejuni to surmount a sudden temperature upshift, allowing the bacterium to survive and adapt its transcriptome to a new steady state.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.