ArticleGenetics2003
The coalescent and infinite-site model of a small multigene family.
Article in Genetics, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
What it found
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Who cites it
41 citing papers in PubMed, 65 citations in OpenAlex.
- Article
- Population Genetics of the Highly PolymorphicGenes · 2019Article
- The Role of Gene Conversion between Transposable Elements in Rewiring Regulatory Networks.Genome biology and evolution · 2019Review
- Effect of Collapsed Duplications on Diversity Estimates: What to Expect.Genome biology and evolution · 2018Article
- Reconciliation feasibility in the presence of gene duplication, loss, and coalescence with multiple individuals per species.BMC bioinformatics · 2017Article
- Interplay of interlocus gene conversion and crossover in segmental duplications under a neutral scenario.G3 (Bethesda, Md.) · 2014Article
- Hard selective sweep and ectopic gene conversion in a gene cluster affording environmental adaptation.PLoS genetics · 2013Article
- Both positive and negative selection pressures contribute to the polymorphism pattern of the duplicated human CYP21A2 gene.PloS one · 2013Article
- Unified modeling of gene duplication, loss, and coalescence using a locus tree.Genome research · 2012Article
- The coalescent with selection on copy number variants.Genetics · 2012Article
- Balancing selection at the tomato RCR3 Guardee gene family maintains variation in strength of pathogen defense.PLoS genetics · 2012Article
- Effects of natural selection and gene conversion on the evolution of human glycophorins coding for MNS blood polymorphisms in malaria-endemic African populations.American journal of human genetics · 2011Article
- Article
- Diversity-enhancing selection acts on a female reproductive protease family in four subspecies of Drosophila mojavensis.Genetics · 2011Article
- Article
- Article
- Gene conversion and DNA sequence polymorphism in the sex-determination gene fog-2 and its paralog ftr-1 in Caenorhabditis elegans.Molecular biology and evolution · 2010Article
- Article
- The evolution of gene duplications: classifying and distinguishing between models.Nature reviews. Genetics · 2010Review
- Population genetic models of duplicated genes.Genetica · 2009Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The infinite-site model of a small multigene family with two duplicated genes is studied. The expectations of the amounts of nucleotide variation within and between two genes and linkage disequilibrium are obtained, and a coalescent-based method for simulating patterns of polymorphism in a small multigene family is developed. The pattern of DNA variation is much more complicated than that in a single-copy gene, which can be simulated by the standard coalescent. Using the coalescent simulation of duplicated genes, the applicability of statistical tests of neutrality to multigene families is considered.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.